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Issue DateTitleAuthor(s)
2018-12-10Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic LeukemiaJing, D; Huang, Y; Liu, X; Sia, KCS; Zhang, JC; Tai, X; Wang, M; Toscan, CE; McCalmont, H; Evans, K; Mayoh, C; Poulos, RC; Span, M; Mi, J; Zhang, C; Wong, JWH; Beck, D; Pimanda, JE; Lock, RB
2016-07-01MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferationHuang, Y; Thoms, JAI; Tursky, ML; Knezevic, K; Beck, D; Chandrakanthan, V; Suryani, S; Olivier, J; Boulton, A; Glaros, EN; Thomas, SR; Lock, RB; MacKenzie, KL; Bushweller, JH; Wong, JWH; Pimanda, JE
2019-12-09A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged LeukemiaKrivtsov, AV; Evans, K; Gadrey, JY; Eschle, BK; Hatton, C; Uckelmann, HJ; Ross, KN; Perner, F; Olsen, SN; Pritchard, T; McDermott, L; Jones, CD; Jing, D; Braytee, A; Chacon, D; Earley, E; McKeever, BM; Claremon, D; Gifford, AJ; Lee, HJ; Teicher, BA; Pimanda, JE; Beck, D; Perry, JA; Smith, MA; McGeehan, GM; Lock, RB; Armstrong, SA
2022-08Mesoderm-derived PDGFRA+ cells regulate the emergence of hematopoietic stem cells in the dorsal aorta.Chandrakanthan, V; Rorimpandey, P; Zanini, F; Chacon, D; Olivier, J; Joshi, S; Kang, YC; Knezevic, K; Huang, Y; Qiao, Q; Oliver, RA; Unnikrishnan, A; Carter, DR; Lee, B; Brownlee, C; Power, C; Brink, R; Mendez-Ferrer, S; Enikolopov, G; Walsh, W; Göttgens, B; Taoudi, S; Beck, D; Pimanda, JE
2017-12-01The non-coding RNA landscape of human hematopoiesis and leukemiaSchwarzer, A; Emmrich, S; Schmidt, F; Beck, D; Ng, M; Reimer, C; Adams, FF; Grasedieck, S; Witte, D; Käbler, S; Wong, JWH; Shah, A; Huang, Y; Jammal, R; Maroz, A; Jongen-Lavrencic, M; Schambach, A; Kuchenbauer, F; Pimanda, JE; Reinhardt, D; Heckl, D; Klusmann, JH
2018-10-01A novel role for Lyl1 in primitive erythropoiesisChiu, SK; Saw, J; Huang, Y; Sonderegger, SE; Wong, NC; Powell, DR; Beck, D; Pimanda, JE; Tremblay, CS; Curtis, DJ
2014-01-01Oncocis: Annotation of cis-regulatory mutations in cancerPerera, D; Chacon, D; Thoms, JA; Poulos, RC; Shlien, A; Beck, D; Campbell, PJ; Pimanda, JE; Wong, JW
2015-04-15Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemiasTursky, ML; Beck, D; Thoms, JAI; Huang, Y; Kumari, A; Unnikrishnan, A; Knezevic, K; Evans, K; Richards, LA; Lee, E; Morris, J; Goldberg, L; Izraeli, S; Wong, JWH; Olivier, J; Lock, RB; MacKenzie, KL; Pimanda, JE
2016-04-19Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cellsChandrakanthan, V; Yeola, A; Kwan, JC; Oliver, RA; Qiao, Q; Kang, YC; Zarzour, P; Beck, D; Boelen, L; Unnikrishnan, A; Villanueva, JE; Nunez, AC; Knezevic, K; Palu, C; Nasrallah, R; Carnell, M; Macmillan, A; Whan, R; Yu, Y; Hardy, P; Grey, ST; Gladbach, A; Delerue, F; Ittner, L; Mobbs, R; Walkley, CR; Purton, LE; Ward, RL; Wong, JWH; Hesson, LB; Walsh, W; Pimanda, JE
2019-11-13Prospective Identification of Acute Myeloid Leukemia Patients Who Benefit from Gene-Expression Based Risk StratificationChacon, D; Braytee, A; Huang, Y; Thoms, J; Subramanian, S; Sauerland, MC; Bohlander, SK; Braess, J; Woermann, BJ; Berdel, WE; Hiddemann, W; Gabrys, B; Metzeler, KH; Herold, T; Pimanda, J; Beck, D
2016-12-01A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional networkUnnikrishnan, A; Guan, YF; Huang, Y; Beck, D; Thoms, JAI; Peirs, S; Knezevic, K; Ma, S; De Walle, IV; De Jong, IDE; Ali, Z; Zhong, L; Raftery, MJ; Taghon, T; Larsson, J; MacKenzie, KL; Van Vlierberghe, P; Wong, JWH; Pimanda, JE
2019-06-15RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomesGuo, D; Lui, GYL; Lai, SL; Wilmott, JS; Tikoo, S; Jackett, LA; Quek, C; Brown, DL; Sharp, DM; Kwan, RYQ; Chacon, D; Wong, JH; Beck, D; van Geldermalsen, M; Holst, J; Thompson, JF; Mann, GJ; Scolyer, RA; Stow, JL; Weninger, W; Haass, NK; Beaumont, KA
2022-08-05Rhometa: Population recombination rate estimation from metagenomic read datasetsKrishnan, S; DeMaere, M; Beck, D; Ostrowski, M; Seymour, J; Darling, A
2023-03Rhometa: Population recombination rate estimation from metagenomic read datasets.Krishnan, S; DeMaere, MZ; Beck, D; Ostrowski, M; Seymour, JR; Darling, AE; Didelot, X
2019-09-05Shared roles for Scl and Lyl1 in murine platelet production and functionChiu, SK; Orive, SL; Moon, MJ; Saw, J; Ellis, S; Kile, BT; Huang, Y; Chacon, D; Pimanda, JE; Beck, D; Hamilton, JR; Tremblay, CS; Curtis, DJ
2020-12Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia.Dun, MD; Mannan, A; Rigby, CJ; Butler, S; Toop, HD; Beck, D; Connerty, P; Sillar, J; Kahl, RGS; Duchatel, RJ; Germon, Z; Faulkner, S; Chi, M; Skerrett-Byrne, D; Murray, HC; Flanagan, H; Almazi, JG; Hondermarck, H; Nixon, B; De Iuliis, G; Chamberlain, J; Alvaro, F; de Bock, CE; Morris, JC; Enjeti, AK; Verrills, NM
2012-04-01Signal analysis for genome-wide maps of histone modifications measured by ChIP-seqBeck, D; Brandl, MB; Boelen, L; Unnikrishnan, A; Pimanda, JE; Wong, JWH
2020-08Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia.Salik, B; Yi, H; Hassan, N; Santiappillai, N; Vick, B; Connerty, P; Duly, A; Trahair, T; Woo, AJ; Beck, D; Liu, T; Spiekermann, K; Jeremias, I; Wang, J; Kavallaris, M; Haber, M; Norris, MD; Liebermann, DA; D'Andrea, RJ; Murriel, C; Wang, JY
2020-08The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1.Carmichael, CL; Wang, J; Nguyen, T; Kolawole, O; Benyoucef, A; De Mazière, C; Milne, AR; Samuel, S; Gillinder, K; Hediyeh-Zadeh, S; Vo, ANQ; Huang, Y; Knezevic, K; McInnes, WRL; Shields, BJ; Mitchell, H; Ritchie, ME; Lammens, T; Lintermans, B; Van Vlierberghe, P; Wong, NC; Haigh, K; Thoms, JAI; Toulmin, E; Curtis, DJ; Oxley, EP; Dickins, RA; Beck, D; Perkins, A; McCormack, MP; Davis, MJ; Berx, G; Zuber, J; Pimanda, JE; Kile, BT; Goossens, S; Haigh, JJ
2019-12-01Transcriptional networks in acute myeloid leukemiaThoms, JAI; Beck, D; Pimanda, JE