Browsing by Author Dalton, JP

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Issue DateTitleAuthor(s)
1-Nov-2008Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophagesDonnelly, S; Stack, CM; O'Neill, SM; Sayed, AA; Williams, DL; Dalton, JP
1-Nov-2012A helminth cathelicidin-like protein suppresses antigen processing and presentation in macrophages via inhibition of lysosomal vATPaseRobinson, MW; Alvarado, R; To, J; Hutchinson, AT; Dowdell, SN; Lund, M; Turnbull, L; Whitchurch, CB; O'Brien, BA; Dalton, JP; Donnelly, S
29-Jan-2010Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3Donnelly, S; O'Neill, SM; Stack, CM; Robinson, MW; Turnbull, L; Whitchurch, C; Dalton, JP
1-Jan-2013Helminth defence molecules-immunomodulators designed by parasites!Robinson, MW; Donnelly, S; Dalton, JP
1-Dec-2008Helminth pathogen cathepsin proteases: it's a family affairRobinson, MW; Dalton, JP; Donnelly, S
1-Jan-2003Helminth vaccines: From mining genomic information for vaccine targets to systems used for protein expressionDalton, JP; Brindley, PJ; Knox, DP; Brady, CP; Hotez, PJ; Donnelly, S; O'Neill, SM; Mulcahy, G; Loukas, A
19-Apr-2004Helminths at mucosal barriers - Interaction with the immune systemMulcahy, G; O'Neill, S; Donnelly, S; Dalton, JP
19-Dec-2011How pathogen-derived cysteine proteases modulate host immune responsesDonnelly, S; Dalton, JP; Robinson, MW
29-Nov-2007Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compoundsSkinner-Adams, TS; Lowther, J; Teuscher, F; Stack, CM; Grembecka, J; Mucha, A; Kafarski, P; Trenholme, KR; Dalton, JP; Gardiner, DL
1-Jan-2014Identification of potent and selective inhibitors of the plasmodium falciparum M18 aspartyl aminopeptidase (PfM18AAP) of human malaria via high-throughput screeningSpicer, T; Fernandez-Vega, V; Chase, P; Scampavia, L; To, J; Dalton, JP; Da Silva, FL; Skinner-Adams, TS; Gardiner, DL; Trenholme, KR; Brown, CL; Ghosh, P; Porubsky, P; Wang, JL; Whipple, DA; Schoenen, FJ; Hodder, P
1-Jan-2017The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophagesAlvarado, R; To, J; Lund, ME; Pinar, A; Mansell, A; Robinson, MW; O'Brien, BA; Dalton, JP; Donnelly, S
1-Dec-2017Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepaticaRuiz-Campillo, MT; Molina-Hernandez, V; Escamilla, A; Stevenson, M; Perez, J; Martinez-Moreno, A; Donnelly, S; Dalton, JP; Cwiklinski, K
25-May-2009Immunological interactions between 2 common pathogens, Th1-inducing Protozoan Toxoplasma gondii and the Th2-inducing helminth fasciola hepaticaMiller, CMD; Smith, NC; Ikin, RJ; Boulter, NR; Dalton, JP; Donnelly, S
1-Aug-2013Immunomodulatory molecules of Fasciola hepatica: Candidates for both vaccine and immunotherapeutic developmentDalton, JP; Robinson, MW; Mulcahy, G; O'Neill, SM; Donnelly, S
19-May-2009The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine proteaseLowther, J; Robinson, MW; Donnelly, SM; Xu, W; Stack, CM; Matthews, JM; Dalton, JP
1-Jan-2015Induction of protective immune responses against Schistosomiasis haematobium in hamsters and mice using cysteine peptidase-based vaccineTallima, H; Dalton, JP; El Ridi, RE
1-Jan-2014Induction of protective immune responses against schistosomiasis using functionally active cysteine peptidasesEl Ridi, R; Tallima, H; Dalton, JP; Donnelly, S
1-Apr-2018Infection by the helminth parasite fasciola hepatica requires rapid regulation of metabolic, virulence, and invasive factors to adjust to its mammalian hostCwiklinski, K; Jewhurst, H; McVeigh, P; Barbour, T; Maule, AG; Tort, J; O'Neill, SM; Robinson, MW; Donnelly, S; Dalton, JP
8-Dec-2009An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: Proteins associated with invasion and infection of the mammalian hostRobinson, MW; Menon, R; Donnelly, SM; Dalton, JP; Ranganathan, S
Jan-2006Isolation and characterisation of cathepsin L1 protease from Fasciola hepatica excretory-secretory products for serodiagnosis of human fasciolosisO'Neill, S; Mulcahy, G; Dalton, JP; Adley, CC