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Showing results 7 to 19 of 19< previous 
Issue DateTitleAuthor(s)
2008-11-01Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophagesDonnelly, S; Stack, CM; O'Neill, SM; Sayed, AA; Williams, DL; Dalton, JP
2010-01-29Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3Donnelly, S; O'Neill, SM; Stack, CM; Robinson, MW; Turnbull, L; Whitchurch, C; Dalton, JP
2007-11-29Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compoundsSkinner-Adams, TS; Lowther, J; Teuscher, F; Stack, CM; Grembecka, J; Mucha, A; Kafarski, P; Trenholme, KR; Dalton, JP; Gardiner, DL
2009-05-19The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine proteaseLowther, J; Robinson, MW; Donnelly, SM; Xu, W; Stack, CM; Matthews, JM; Dalton, JP
2009-06-16The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: Importance of active site metal ions in the binding of substrates and inhibitorsMaric, S; Donnelly, SM; Robinson, MW; Skinner-Adams, T; Trenholme, KR; Gardiner, DL; Dalton, JP; Stack, CM; Lowther, J
2007-10-19The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparumTeuscher, F; Lowther, J; Skinner-Adams, TS; Spielmann, T; Dixon, MWA; Stack, CM; Donnelly, S; Mucha, A; Kafarski, P; Vassiliou, S; Gardiner, DL; Dalton, JP; Trenholme, KR
2007-06-01The major secreted cathepsin L1 protease of the liver fluke, Fasciola hepatica: A Leu<sup>-12</sup> to Pro<sup>-12</sup> replacement in the nonconserved C-terminal region of the prosegment prevents complete enzyme autoactivation and allows definition of the molecular events in prosegment removalStack, CM; Donnelly, S; Lowther, J; Xu, W; Collins, PR; Brinen, LS; Dalton, JP
2006-01-20Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites: Target for the antimalarial activity of bestatinGardiner, DL; Trenholme, KR; Skinner-Adams, TS; Stack, CM; Dalton, JP
2016-10-01A Plasmodium falciparum S33 proline aminopeptidase is associated with changes in erythrocyte deformabilityda Silva, FL; Dixon, MWA; Stack, CM; Teuscher, F; Taran, E; Jones, MK; Lovas, E; Tilley, L; Brown, CL; Trenholme, KR; Dalton, JP; Gardiner, DL; Skinner-Adams, TS
2008-06-01Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: Expansion of a repertoire of virulence-associated factorsRobinson, MW; Tort, JF; Lowther, J; Donnelly, SM; Wong, E; Xu, W; Stack, CM; Padula, M; Herbert, B; Dalton, JP
2008-04-11Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepaticaStack, CM; Caffrey, CR; Donnelly, SM; Seshaadri, A; Lowther, J; Tort, JF; Collins, PR; Robinson, MW; Xu, W; McKerrow, JH; Craik, CS; Geiger, SR; Marion, R; Brinen, LS; Dalton, JP
2009-02-24Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidaseMcGowan, S; Porter, CJ; Lowther, J; Stack, CM; Golding, SJ; Skinner-Adams, TS; Trenholme, KR; Teuscher, F; Donnelly, SM; Grembecka, J; Mucha, A; Kafarski, P; Degori, R; Buckle, AM; Gardiner, DL; Whisstock, JC; Dalton, JP
2010-02-09Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidasesMcGowan, S; Oellig, CA; Birru, WA; Caradoc-Davies, TT; Stack, CM; Lowther, J; Skinner-Adams, T; Mucha, A; Kafarski, P; Grembecka, J; Trenholme, KR; Buckle, AM; Gardiner, DL; Dalton, JP; Whisstock, JC