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Showing results 5 to 12 of 12
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Issue Date
Title
Author(s)
2021-12-31
Design, synthesis and biological evaluation of P2-modified proline analogues targeting the HtrA serine protease in Chlamydia.
Hwang, J
;
Strange, N
;
Mazraani, R
;
Phillips, MJ
;
Gamble, AB
;
Huston, WM
;
Tyndall, JDA
2013-08-01
Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatis
Gloeckl, S
;
Ong, VA
;
Patel, P
;
Tyndall, JDA
;
Timms, P
;
Beagley, KW
;
Allan, JA
;
Armitage, CW
;
Turnbull, L
;
Whitchurch, CB
;
Merdanovic, M
;
Ehrmann, M
;
Powers, JC
;
Oleksyszyn, J
;
Verdoes, M
;
Bogyo, M
;
Huston, WM
2021-11
Optimization of peptide-based inhibitors targeting the HtrA serine protease in Chlamydia: Design, synthesis and biological evaluation of pyridone-based and N-Capping group-modified analogues.
Hwang, J
;
Strange, N
;
Phillips, MJA
;
Krause, AL
;
Heywood, A
;
Gamble, AB
;
Huston, WM
;
Tyndall, JDA
2018-07-01
Proteases and protease inhibitors in infectious diseases
Agbowuro, AA
;
Huston, WM
;
Gamble, AB
;
Tyndall, JDA
2013-12-01
Proteolytic activation of Chlamydia trachomatis HTRA is mediated by PDZ1 domain interactions with protease domain loops L3 and LC and beta strand β5
Marsh, JW
;
Lott, WB
;
Tyndall, JDA
;
Huston, WWM
2018-03-22
Stereochemical basis for the anti-chlamydial activity of the phosphonate protease inhibitor JO146
Agbowuro, AA
;
Mazraani, R
;
McCaughey, LC
;
Huston, WM
;
Gamble, AB
;
Tyndall, JDA
2019-09-15
Structure-activity analysis of peptidic Chlamydia HtrA inhibitors
Agbowuro, AA
;
Hwang, J
;
Peel, E
;
Mazraani, R
;
Springwald, A
;
Marsh, JW
;
McCaughey, L
;
Gamble, AB
;
Huston, WM
;
Tyndall, JDA
2011-09-08
Unique residues involved in activation of the multitasking protease/chaperone HtrA from Chlamydia trachomatis
Huston, WM
;
Tyndall, JDA
;
Lott, WB
;
Stansfield, SH
;
Timms, P