Showing results 1 to 20 of 55
next >
Issue Date | Title | Author(s) |
2023-12-21 | Protonophoric and mitochondrial uncoupling activity of aryl-carbamate substituted fatty acids. | MacDermott-Opeskin, H; Clarke, C; Wu, X; Roseblade, A; York, E; Pacchini, E; Roy, R; Cranfield, C; Gale, PA; O'Mara, ML; Murray, M; Rawling, T |
2023-09 | An update on inflammation in uveal melanoma. | Liau, S; Wang, JZ; Zagarella, E; Paulus, P; Dang, NHQH; Rawling, T; Murray, M; Zhou, F |
2023-08-30 | Sorafenib plus intensive chemotherapy in newly diagnosed FLT3-ITD AML:a randomized, placebo-controlled study by the ALLG. | Loo, S; Roberts, AW; Anstee, NS; Kennedy, GA; He, SZ-X; Schwarer, AP; Enjeti, AK; D'Rozario, J; Marlton, P; Bilmon, I; Taper, JM; Cull, G; Tiley, C; Verner, E; Hahn, U; Hiwase, DK; Iland, HJ; Murphy, NE; Ramanathan, S; Reynolds, J; Ong, DM; Tiong, IS; Wall, M; Murray, M; Rawling, T; Leadbetter, J; Rowley, L; Latimer, M; Yuen, SLS; Ting, SB; Fong, CY; Morris, KL; Bajel, A; Seymour, JF; Levis, MJ; Wei, AH |
2023-08-02 | Novel Phenylene Lipids That Are Positive Allosteric Modulators of Glycine Receptors and Inhibitors of Glycine Transporter 2. | Gallagher, CI; Frangos, ZJ; Sheipouri, D; Shimmon, S; Duman, M-N; Jayakumar, S; Cioffi, CL; Rawling, T; Vandenberg, RJ |
2023-07-31 | Fatty Acid-Activated Proton Transport by Bisaryl Anion Transporters Depolarises Mitochondria and Reduces the Viability of MDA-MB-231 Breast Cancer Cells. | York, E; McNaughton, DA; Duman, M-N; Gale, PA; Rawling, T |
2023-07-14 | Aromatic long chain cations of amphiphilic ionic liquids permeabilise the inner mitochondrial membrane and induce mitochondrial dysfunction at cytotoxic concentrations | Duman, MN; Angeloski, A; Johnson, MS; Rawling, T |
2023-01-15 | Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids. | Rahman, MK; Umashankar, B; Choucair, H; Pazderka, C; Bourget, K; Chen, Y; Dunstan, CR; Rawling, T; Murray, M |
2022-09 | Peripheral administration of selective GlyT2 inhibitor, oleoyl-D-lysine, reverses chronic neuropathic pain but not acute or inflammatory pain in male mice | Wilson, BS; Peiser-Oliver, J; Gillis, A; Evans, S; Alamein, C; Mostyn, SN; Shimmon, S; Rawling, T; Christie, MJ; Vandenberg, RJ; Mohammadi, SA |
2022-08-19 | Structure-Activity Relationship and Mechanistic Studies of Bisaryl Urea Anticancer Agents Indicate Mitochondrial Uncoupling by a Fatty Acid-Activated Mechanism. | York, E; McNaughton, DA; Roseblade, A; Cranfield, CG; Gale, PA; Rawling, T |
2022-02-01 | The aryl-ureido fatty acid CTU activates endoplasmic reticulum stress and PERK/NOXA-mediated apoptosis in tumor cells by a dual mitochondrial-targeting mechanism. | Choucair, H; Rahman, MK; Umashankar, B; Al-Zubaidi, Y; Bourget, K; Chen, Y; Dunstan, C; Rawling, T; Murray, M |
2021-10 | PTU, a novel ureido-fatty acid, inhibits MDA-MB-231 cell invasion and dissemination by modulating Wnt5a secretion and cytoskeletal signaling. | Al-Zubaidi, Y; Chen, Y; Khalilur Rahman, M; Umashankar, B; Choucair, H; Bourget, K; Chung, L; Qi, Y; Witting, PK; Anderson, RL; O'Neill, GM; Dunstan, CR; Rawling, T; Murray, M |
2021-02-05 | Differential inhibition of human CYP2C8 and molecular docking interactions elicited by sorafenib and its major N-oxide metabolite. | Nair, PC; Gillani, TB; Rawling, T; Murray, M |
2021-02-03 | Mitochondrial uncoupler SHC517 reverses obesity in mice without affecting food intake. | Chen, S-Y; Beretta, M; Alexopoulos, SJ; Shah, DP; Olzomer, EM; Hargett, SR; Childress, ES; Salamoun, JM; Aleksovska, I; Roseblade, A; Cranfield, C; Rawling, T; Quinlan, KGR; Morris, MJ; Tucker, SP; Santos, WL; Hoehn, KL |
2021-01-12 | The allosteric inhibition of glycine transporter 2 by bioactive lipid analgesics is controlled by penetration into a deep lipid cavity. | Wilson, KA; Mostyn, SN; Frangos, ZJ; Shimmon, S; Rawling, T; Vandenberg, RJ; O'Mara, ML |
2020-10 | Identification of N-acyl amino acids that are positive allosteric modulators of glycine receptors. | Gallagher, CI; Sheipouri, D; Shimmon, S; Rawling, T; Vandenberg, RJ |
2020-08-16 | Expansion of the structure-activity relationship of branched chain fatty acids: effect of unsaturation and branching group size on anticancer activity. | Roy, R; Roseblade, A; Rawling, T |
2020-05 | Photoswitchable ORG25543 Congener Enables Optical Control of Glycine Transporter 2. | Mostyn, SN; Sarker, S; Muthuraman, P; Raja, A; Shimmon, S; Rawling, T; Cioffi, CL; Vandenberg, RJ |
2020 | Omega-3 Polyunsaturated Fatty Acid Derived Lipid Mediators and Their Application in Drug Discovery. | Pazderka, CW; Oliver, B; Murray, M; Rawling, T |
2020 | Antiproliferative activities of tricyclic amides derived from β-caryophyllene via the Ritter reaction against MDA-MB-231 breast cancer cells | Xu, X; Roseblade, A; Rawling, T; Ung, AT |
2019-11-01 | Inhibition of Hepatic CYP2D6 by the Active N-Oxide Metabolite of Sorafenib | Murray, M; Gillani, TB; Rawling, T; Nair, PC |