Browsing byAuthorTimens, W

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Issue DateTitleAuthor(s)
2023-11A bronchial gene signature specific for severe COPD that is retained in the nose.van Nijnatten, J; Faiz, A; Timens, W; Guryev, V; Slebos, D-J; Klooster, K; Hartman, JE; Kole, T; Choy, DF; Chakrabarti, A; Grimbaldeston, M; Rosenberger, CM; Kerstjens, H; Brandsma, C-A; van den Berge, M
2023-09-14IL-33 Expression Is Lower in Current Smokers at Both Transcriptomic and Protein Level.Faiz, A; Mahbub, RM; Boedijono, FS; Tomassen, MI; Kooistra, W; Timens, W; Nawijn, M; Hansbro, PM; Johansen, MD; Pouwels, SD; Heijink, IH; Massip, F; de Biase, MS; Schwarz, RF; Adcock, IM; Chung, KF; van der Does, A; Hiemstra, PS; Goulaouic, H; Xing, H; Abdulai, R; de Rinaldis, E; Cunoosamy, D; Harel, S; Lederer, D; Nivens, MC; Wark, PA; Kerstjens, HAM; Hylkema, MN; Brandsma, C-A; van den Berge, M; Cambridge Lung Cancer Early Detection Programme,
2023-07Longitudinal Effects of 1-Year Smoking Cessation on Human Bronchial Epithelial Transcriptome.Rathnayake, SNH; Ditz, B; Willemse, BWM; National Heart, Lung, and Blood Institute LungMAP Consortium,; Timens, W; Kooistra, W; Heijink, IH; Oliver, BGG; van den Berge, M; Faiz, A
2023-06An integrated cell atlas of the lung in health and disease.Sikkema, L; Ramírez-Suástegui, C; Strobl, DC; Gillett, TE; Zappia, L; Madissoon, E; Markov, NS; Zaragosi, L-E; Ji, Y; Ansari, M; Arguel, M-J; Apperloo, L; Banchero, M; Bécavin, C; Berg, M; Chichelnitskiy, E; Chung, M-I; Collin, A; Gay, ACA; Gote-Schniering, J; Hooshiar Kashani, B; Inecik, K; Jain, M; Kapellos, TS; Kole, TM; Leroy, S; Mayr, CH; Oliver, AJ; von Papen, M; Peter, L; Taylor, CJ; Walzthoeni, T; Xu, C; Bui, LT; De Donno, C; Dony, L; Faiz, A; Guo, M; Gutierrez, AJ; Heumos, L; Huang, N; Ibarra, IL; Jackson, ND; Kadur Lakshminarasimha Murthy, P; Lotfollahi, M; Tabib, T; Talavera-López, C; Travaglini, KJ; Wilbrey-Clark, A; Worlock, KB; Yoshida, M; Lung Biological Network Consortium,; van den Berge, M; Bossé, Y; Desai, TJ; Eickelberg, O; Kaminski, N; Krasnow, MA; Lafyatis, R; Nikolic, MZ; Powell, JE; Rajagopal, J; Rojas, M; Rozenblatt-Rosen, O; Seibold, MA; Sheppard, D; Shepherd, DP; Sin, DD; Timens, W; Tsankov, AM; Whitsett, J; Xu, Y; Banovich, NE; Barbry, P; Duong, TE; Falk, CS; Meyer, KB; Kropski, JA; Pe'er, D; Schiller, HB; Tata, PR; Schultze, JL; Teichmann, SA; Misharin, AV; Nawijn, MC; Luecken, MD; Theis, FJ
2023-05-11Smoking increases expression of the SARS-CoV-2 spike protein-binding long ACE2 isoform in bronchial epithelium.Pouwels, SD; van den Berge, M; Vasse, GF; Timens, W; Brandsma, C-A; Aliee, H; Hiemstra, PS; Guryev, V; Faiz, A
2023-04-01A proteomics approach to identify COPD-related changes in lung fibroblastsBekker, NJ; van Pijkeren, A; Wolters, JC; Sánchez Brotons, A; Guryev, V; Woldhuis, RR; Bischoff, R; Alkema, W; Horvatovich, P; van Nijnatten, JLL; van den Berge, M; Timens, W; Brandsma, C-A
2023-01-21Gene expression profiles in mesenchymal stromal cells from bone marrow, adipose tissue and lung tissue of COPD patients and controls.Kruk, D; Yeung, ACY; Faiz, A; Ten Hacken, NHT; Timens, W; van Kuppevelt, TH; Daamen, W; Hof, D; Harmsen, MC; Rojas, M; Heijink, IH
2023Th2 high and mast cell gene signatures are associated with corticosteroid sensitivity in COPD.Faiz, A; Pavlidis, S; Kuo, C-H; Rowe, A; Hiemstra, PS; Timens, W; Berg, M; Wisman, M; Guo, Y-K; Djukanović, R; Sterk, P; Meyer, KB; Nawijn, MC; Adcock, I; Chung, KF; van den Berge, M
2022-11-22Smoking induces shifts in cellular composition and transcriptome within the bronchial mucus barrier.Rathnayake, SNH; Ditz, B; van Nijnatten, J; Sadaf, T; Hansbro, PM; Brandsma, CA; Timens, W; van Schadewijk, A; Hiemstra, PS; Ten Hacken, NHT; Oliver, B; Kerstjens, HAM; van den Berge, M; Faiz, A
2022-09-02Early transcriptional responses of bronchial epithelial cells to whole cigarette smoke mirror those of in-vivo exposed human bronchial mucosa.van der Does, AM; Mahbub, RM; Ninaber, DK; Rathnayake, SNH; Timens, W; van den Berge, M; Aliee, H; Theis, FJ; Nawijn, MC; Hiemstra, PS; Faiz, A
2022-08Association of bronchial steroid inducible methylation quantitative trait loci with asthma and chronic obstructive pulmonary disease treatment response.Slob, EMA; Faiz, A; van Nijnatten, J; Vijverberg, SJH; Longo, C; Kutlu, M; Chew, FT; Sio, YY; Herrera-Luis, E; Espuela-Ortiz, A; Perez-Garcia, J; Pino-Yanes, M; Burchard, EG; Potočnik, U; Gorenjak, M; Palmer, C; Maroteau, C; Turner, S; Verhamme, K; Karimi, L; Mukhopadhyay, S; Timens, W; Hiemstra, PS; Pijnenburg, MW; Neighbors, M; Grimbaldeston, MA; Tew, GW; Brandsma, CA; Berce, V; Aliee, H; Theis, F; Sin, DD; Li, X; van den Berge, M; Maitland-van der Zee, AH; Koppelman, GH
2022-04-04High miR203a-3p and miR-375 expression in the airways of smokers with and without COPD.van Nijnatten, J; Brandsma, C-A; Steiling, K; Hiemstra, PS; Timens, W; van den Berge, M; Faiz, A
2022-03-03The relation between age and airway epithelial barrier function.de Vries, M; Nwozor, KO; Muizer, K; Wisman, M; Timens, W; van den Berge, M; Faiz, A; Hackett, T-L; Heijink, IH; Brandsma, CA
2022-01-01Identification of asthma associated microRNAs in bronchial biopsies.Roffel, MP; Boudewijn, IM; van Nijnatten, JLL; Faiz, A; Vermeulen, CJ; van Oosterhout, AJ; Affleck, K; Timens, W; Bracke, KR; Maes, T; Heijink, IH; Brandsma, C-A; van den Berge, M
2022-01Bronchial gene expression signature associated with rate of subsequent FEV1 decline in individuals with and at risk of COPD.Becker, EJ; Faiz, A; van den Berge, M; Timens, W; Hiemstra, PS; Clark, K; Liu, G; Xiao, X; Alekseyev, YO; O'Connor, G; Lam, S; Spira, A; Lenburg, ME; Steiling, K
2022The Microbiome in Bronchial Biopsies from Smokers and Ex-Smokers with Stable COPD - A Metatranscriptomic Approach.Ditz, B; Boekhoudt, J; Couto, N; Brandsma, CA; Hiemstra, PS; Tew, GW; Neighbors, M; Grimbaldeston, MA; Timens, W; Kerstjens, HAM; Rossen, JWA; Guryev, V; van den Berge, M; Faiz, A
2021-10-26Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways.Aliee, H; Massip, F; Qi, C; Stella de Biase, M; van Nijnatten, J; Kersten, ETG; Kermani, NZ; Khuder, B; Vonk, JM; Vermeulen, RCH; U-BIOPRED study group,; Cambridge Lung Cancer Early Detection Programme,; INER-Ciencias Mexican Lung Program,; Neighbors, M; Tew, GW; Grimbaldeston, MA; Ten Hacken, NHT; Hu, S; Guo, Y; Zhang, X; Sun, K; Hiemstra, PS; Ponder, BA; Mäkelä, MJ; Malmström, K; Rintoul, RC; Reyfman, PA; Theis, FJ; Brandsma, C-A; Adcock, IM; Timens, W; Xu, C-J; van den Berge, M; Schwarz, RF; Koppelman, GH; Nawijn, MC; Faiz, A
2021-04-01LONGITUDINAL EFFECTS OF 12 MONTHS SMOKING CESSATION ON DNA METHYLATION AND GENE EXPRESSION IN BRONCHIAL BIOPSIESRathnayake, S; Vermeulen, C; Ten Hacken, N; Timens, W; Kooistra, W; Heijink, H; Brandsma, C; Oliver, B; Van den Berge, M; Faiz, A
2021-04Comparison of genome-wide gene expression profiling by RNA Sequencing versus microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?Ditz, B; Boekhoudt, JG; Aliee, H; Theis, FJ; Nawijn, M; Brandsma, C-A; Hiemstra, PS; Timens, W; Tew, GW; Grimbaldeston, MA; Neighbors, M; Guryev, V; van den Berge, M; Faiz, A
2021-01-01RAGE and TLR4 differentially regulate airway hyperresponsiveness: implications for COPD.Allam, VSRR; Faiz, A; Lam, M; Rathnayake, SNH; Ditz, B; Pouwels, SD; Brandsma, C-A; Timens, W; Hiemstra, PS; Tew, GW; Neighbors, M; Grimbaldeston, M; van den Berge, M; Donnelly, S; Phipps, S; Bourke, JE; Sukkar, MB