Browsing by Author Trenholme, KR

Showing results 1 to 9 of 9
Issue DateTitleAuthor(s)
2-May-2017The development of sexual stage malaria gametocytes in a Wave BioreactorDemanga, CG; Eng, JWL; Gardiner, DL; Roth, A; Butterworth, A; Adams, JH; Trenholme, KR; Dalton, JP
1-Oct-2016A Plasmodium falciparum S33 proline aminopeptidase is associated with changes in erythrocyte deformabilityda Silva, FL; Dixon, MWA; Stack, CM; Teuscher, F; Taran, E; Jones, MK; Lovas, E; Tilley, L; Brown, CL; Trenholme, KR; Dalton, JP; Gardiner, DL; Skinner-Adams, TS
1-Jan-2014Identification of potent and selective inhibitors of the plasmodium falciparum M18 aspartyl aminopeptidase (PfM18AAP) of human malaria via high-throughput screeningTo, J; Dalton, JP; Da Silva, FL; Skinner-Adams, TS; Gardiner, DL; Trenholme, KR; Brown, CL; Ghosh, P; Porubsky, P; Wang, JL; Whipple, DA; Schoenen, FJ; Hodder, P
28-Sep-2012X-ray crystal structure and specificity of the plasmodium falciparum malaria aminopeptidase PfM18AAPSivaraman, KK; Oellig, CA; Huynh, K; Atkinson, SC; Poreba, M; Perugini, MA; Trenholme, KR; Gardiner, DL; Salvesen, G; Drag, M; Dalton, JP; Whisstock, JC; McGowan, S
25-Jun-2012Anti-malaria drug development targeting the M1 alanyl and M17 leucyl aminopeptidasesThivierge, K; Mathew, RT; Nsangou, DMM; Da Silva, F; Cotton, S; Skinner-Adams, TS; Trenholme, KR; Brown, CL; Stack, CM; Gardiner, DL; Dalton, JP
16-Feb-2012Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparumTrenholme, KR; Gardiner, DL; Whisstock, JC; To, J; Salvesen, GS; Dalton, JP; Drag, M
9-Feb-2010Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidasesStack, CM; Lowther, J; Skinner-Adams, T; Mucha, A; Kafarski, P; Grembecka, J; Trenholme, KR; Buckle, AM; Gardiner, DL; Dalton, JP; Whisstock, JC
16-Jun-2009The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: Importance of active site metal ions in the binding of substrates and inhibitorsTrenholme, KR; Gardiner, DL; Dalton, JP; Stack, CM; Lowther, J
24-Feb-2009Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidaseTrenholme, KR; Teuscher, F; Donnelly, SM; Grembecka, J; Mucha, A; Kafarski, P; Degori, R; Buckle, AM; Gardiner, DL; Whisstock, JC; Dalton, JP