Browsing byAuthorWhisstock, JC

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Issue DateTitleAuthor(s)
2022-08Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism.Chang, Y-G; Lupton, CJ; Bayly-Jones, C; Keen, AC; D'Andrea, L; Lucato, CM; Steele, JR; Venugopal, H; Schittenhelm, RB; Whisstock, JC; Halls, ML; Ellisdon, AM
2012-09-28X-ray crystal structure and specificity of the plasmodium falciparum malaria aminopeptidase PfM18AAPSivaraman, KK; Oellig, CA; Huynh, K; Atkinson, SC; Poreba, M; Perugini, MA; Trenholme, KR; Gardiner, DL; Salvesen, G; Drag, M; Dalton, JP; Whisstock, JC; McGowan, S
2012-02-16Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparumPoreba, M; McGowan, S; Skinner-Adams, TS; Trenholme, KR; Gardiner, DL; Whisstock, JC; To, J; Salvesen, GS; Dalton, JP; Drag, M
2011-08-23Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidasesHarbut, MB; Velmourougane, G; Dalal, S; Reiss, G; Whisstock, JC; Onder, O; Brisson, D; McGowan, S; Klemba, M; Greenbaum, DC
2010-02-09Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidasesMcGowan, S; Oellig, CA; Birru, WA; Caradoc-Davies, TT; Stack, CM; Lowther, J; Skinner-Adams, T; Mucha, A; Kafarski, P; Grembecka, J; Trenholme, KR; Buckle, AM; Gardiner, DL; Dalton, JP; Whisstock, JC
2009-02-24Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidaseMcGowan, S; Porter, CJ; Lowther, J; Stack, CM; Golding, SJ; Skinner-Adams, TS; Trenholme, KR; Teuscher, F; Donnelly, SM; Grembecka, J; Mucha, A; Kafarski, P; Degori, R; Buckle, AM; Gardiner, DL; Whisstock, JC; Dalton, JP