Browsing byAuthorKnezevic, K

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Showing results 1 to 13 of 13
Issue DateTitleAuthor(s)
2013-01-01Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemiaDiffner, E; Beck, D; Gudgin, E; Thoms, JAI; Knezevic, K; Pridans, C; Foster, S; Goode, D; Lim, WK; Boelen, L; Metzeler, KH; Micklem, G; Bohlander, SK; Buske, C; Burnett, A; Ottersbach, K; Vassiliou, GS; Olivier, J; Wong, JWH; Göttgens, B; Huntly, BJ; Pimanda, JE
2016-01-01Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in DhfrThoms, JAI; Knezevic, K; Liu, JJ; Glaros, EN; Thai, T; Qiao, Q; Campbell, H; Packham, D; Huang, Y; Papathanasiou, P; Tunningley, R; Whittle, B; Yeung, AWS; Chandrakanthan, V; Hesson, L; Chen, V; Wong, JWH; Purton, LE; Ward, RL; Thomas, SR; Pimanda, JE
2018-09-15Disruption of a 35 KB enhancer impairs CTCF binding and MLH1 expression in colorectal cellsLiu, Q; Thoms, JAI; Nunez, AC; Huang, Y; Knezevic, K; Packham, D; Poulos, RC; Williams, R; Beck, D; Hawkins, NJ; Ward, RL; Wong, JWH; Hesson, LB; Sloane, MA; Pimanda, JE
2021-06-01Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells.Thoms, JAI; Truong, P; Subramanian, S; Knezevic, K; Harvey, G; Huang, Y; Seneviratne, JA; Carter, DR; Joshi, S; Skhinas, J; Chacon, D; Shah, A; de Jong, I; Beck, D; Gottgens, B; Larsson, J; Wong, JWH; Zanini, F; Pimanda, JE
2013-10-10Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemiaGoldberg, L; Tijssen, MR; Birger, Y; Hannah, RL; Kinston, SJ; Schütte, J; Beck, D; Knezevic, K; Schiby, G; Jacob-Hirsch, J; Biran, A; Kloog, Y; Marcucci, G; Bloomfield, CD; Aplan, PD; Pimanda, JE; Göttgens, B; Izraeli, S
2013-01-01Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genesBeck, D; Thoms, JAI; Perera, D; Schütte, J; Unnikrishnan, A; Knezevic, K; Kinston, SJ; Wilson, NK; O'Brien, TA; Göttgens, B; Wong, JWH; Pimanda, JE
2016-10-13Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probesNasrallah, R; Fast, EM; Solaimani, P; Knezevic, K; Eliades, A; Patel, R; Thambyrajah, R; Unnikrishnan, A; Thoms, J; Beck, D; Vink, CS; Smith, A; Wong, J; Shepherd, M; Kent, D; Roychoudhuri, R; Paul, F; Klippert, J; Hammes, A; Willnow, T; Göttgens, B; Dzierzak, E; Zon, LI; Lacaud, G; Kouskoff, V; Pimanda, JE
2017-07-18Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic SyndromesUnnikrishnan, A; Papaemmanuil, E; Beck, D; Deshpande, NP; Verma, A; Kumari, A; Woll, PS; Richards, LA; Knezevic, K; Chandrakanthan, V; Thoms, JAI; Tursky, ML; Huang, Y; Ali, Z; Olivier, J; Galbraith, S; Kulasekararaj, AG; Tobiasson, M; Karimi, M; Pellagatti, A; Wilson, SR; Lindeman, R; Young, B; Ramakrishna, R; Arthur, C; Stark, R; Crispin, P; Curnow, J; Warburton, P; Roncolato, F; Boultwood, J; Lynch, K; Jacobsen, SEW; Mufti, GJ; Hellstrom-Lindberg, E; Wilkins, MR; MacKenzie, KL; Wong, JWH; Campbell, PJ; Pimanda, JE
2016-07-01MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferationHuang, Y; Thoms, JAI; Tursky, ML; Knezevic, K; Beck, D; Chandrakanthan, V; Suryani, S; Olivier, J; Boulton, A; Glaros, EN; Thomas, SR; Lock, RB; MacKenzie, KL; Bushweller, JH; Wong, JWH; Pimanda, JE
2015-04-15Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemiasTursky, ML; Beck, D; Thoms, JAI; Huang, Y; Kumari, A; Unnikrishnan, A; Knezevic, K; Evans, K; Richards, LA; Lee, E; Morris, J; Goldberg, L; Izraeli, S; Wong, JWH; Olivier, J; Lock, RB; MacKenzie, KL; Pimanda, JE
2016-04-19Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cellsChandrakanthan, V; Yeola, A; Kwan, JC; Oliver, RA; Qiao, Q; Kang, YC; Zarzour, P; Beck, D; Boelen, L; Unnikrishnan, A; Villanueva, JE; Nunez, AC; Knezevic, K; Palu, C; Nasrallah, R; Carnell, M; Macmillan, A; Whan, R; Yu, Y; Hardy, P; Grey, ST; Gladbach, A; Delerue, F; Ittner, L; Mobbs, R; Walkley, CR; Purton, LE; Ward, RL; Wong, JWH; Hesson, LB; Walsh, W; Pimanda, JE
2016-12-01A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional networkUnnikrishnan, A; Guan, YF; Huang, Y; Beck, D; Thoms, JAI; Peirs, S; Knezevic, K; Ma, S; De Walle, IV; De Jong, IDE; Ali, Z; Zhong, L; Raftery, MJ; Taghon, T; Larsson, J; MacKenzie, KL; Van Vlierberghe, P; Wong, JWH; Pimanda, JE
2020-08The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1.Carmichael, CL; Wang, J; Nguyen, T; Kolawole, O; Benyoucef, A; De Mazière, C; Milne, AR; Samuel, S; Gillinder, K; Hediyeh-Zadeh, S; Vo, ANQ; Huang, Y; Knezevic, K; McInnes, WRL; Shields, BJ; Mitchell, H; Ritchie, ME; Lammens, T; Lintermans, B; Van Vlierberghe, P; Wong, NC; Haigh, K; Thoms, JAI; Toulmin, E; Curtis, DJ; Oxley, EP; Dickins, RA; Beck, D; Perkins, A; McCormack, MP; Davis, MJ; Berx, G; Zuber, J; Pimanda, JE; Kile, BT; Goossens, S; Haigh, JJ