Browsing byAuthorThoms, JAI

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Showing results 1 to 15 of 15
Issue DateTitleAuthor(s)
2013-01-01Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemiaDiffner, E; Beck, D; Gudgin, E; Thoms, JAI; Knezevic, K; Pridans, C; Foster, S; Goode, D; Lim, WK; Boelen, L; Metzeler, KH; Micklem, G; Bohlander, SK; Buske, C; Burnett, A; Ottersbach, K; Vassiliou, GS; Olivier, J; Wong, JWH; Göttgens, B; Huntly, BJ; Pimanda, JE
2017-09-01Annotating function to differentially expressed LincRNAs in myelodysplastic syndrome using a network-based methodLiu, K; Beck, D; Thoms, JAI; Liu, L; Zhao, W; Pimanda, JE; Zhou, X
2016-01-01Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in DhfrThoms, JAI; Knezevic, K; Liu, JJ; Glaros, EN; Thai, T; Qiao, Q; Campbell, H; Packham, D; Huang, Y; Papathanasiou, P; Tunningley, R; Whittle, B; Yeung, AWS; Chandrakanthan, V; Hesson, L; Chen, V; Wong, JWH; Purton, LE; Ward, RL; Thomas, SR; Pimanda, JE
2018-09-15Disruption of a 35 KB enhancer impairs CTCF binding and MLH1 expression in colorectal cellsLiu, Q; Thoms, JAI; Nunez, AC; Huang, Y; Knezevic, K; Packham, D; Poulos, RC; Williams, R; Beck, D; Hawkins, NJ; Ward, RL; Wong, JWH; Hesson, LB; Sloane, MA; Pimanda, JE
2021-06-01Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells.Thoms, JAI; Truong, P; Subramanian, S; Knezevic, K; Harvey, G; Huang, Y; Seneviratne, JA; Carter, DR; Joshi, S; Skhinas, J; Chacon, D; Shah, A; de Jong, I; Beck, D; Gottgens, B; Larsson, J; Wong, JWH; Zanini, F; Pimanda, JE
2018-02-01A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patientsBeck, D; Thoms, JAI; Palu, C; Herold, T; Shah, A; Olivier, J; Boelen, L; Huang, Y; Chacon, D; Brown, A; Babic, M; Hahn, C; Perugini, M; Zhou, X; Huntly, BJ; Schwarzer, A; Klusmann, JH; Berdel, WE; Wörmann, B; Büchner, T; Hiddemann, W; Bohlander, SK; To, LB; Scott, HS; Lewis, ID; D'Andrea, RJ; Wong, JWH; Pimanda, JE
2013-01-01Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genesBeck, D; Thoms, JAI; Perera, D; Schütte, J; Unnikrishnan, A; Knezevic, K; Kinston, SJ; Wilson, NK; O'Brien, TA; Göttgens, B; Wong, JWH; Pimanda, JE
2019-02-26HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cellsKumar, P; Beck, D; Galeev, R; Thoms, JAI; Talkhoncheh, MS; de Jong, I; Unnikrishnan, A; Baudet, A; Subramaniam, A; Pimanda, JE; Larsson, J
2021-01-13Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidineYeola, A; Subramanian, S; Oliver, RA; Lucas, CA; Thoms, JAI; Yan, F; Olivier, J; Chacon, D; Tursky, ML; Srivastava, P; Potas, JR; Hung, T; Power, C; Hardy, P; D., D; Kilian, KA; McCarroll, J; Kavallaris, M; Hesson, LB; Beck, D; Curtis, DJ; Wong, JWH; Hardeman, EC; Walsh, WR; Mobbs, R; Chandrakanthan, V; Pimanda, JE
2017-07-18Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic SyndromesUnnikrishnan, A; Papaemmanuil, E; Beck, D; Deshpande, NP; Verma, A; Kumari, A; Woll, PS; Richards, LA; Knezevic, K; Chandrakanthan, V; Thoms, JAI; Tursky, ML; Huang, Y; Ali, Z; Olivier, J; Galbraith, S; Kulasekararaj, AG; Tobiasson, M; Karimi, M; Pellagatti, A; Wilson, SR; Lindeman, R; Young, B; Ramakrishna, R; Arthur, C; Stark, R; Crispin, P; Curnow, J; Warburton, P; Roncolato, F; Boultwood, J; Lynch, K; Jacobsen, SEW; Mufti, GJ; Hellstrom-Lindberg, E; Wilkins, MR; MacKenzie, KL; Wong, JWH; Campbell, PJ; Pimanda, JE
2016-07-01MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferationHuang, Y; Thoms, JAI; Tursky, ML; Knezevic, K; Beck, D; Chandrakanthan, V; Suryani, S; Olivier, J; Boulton, A; Glaros, EN; Thomas, SR; Lock, RB; MacKenzie, KL; Bushweller, JH; Wong, JWH; Pimanda, JE
2015-04-15Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemiasTursky, ML; Beck, D; Thoms, JAI; Huang, Y; Kumari, A; Unnikrishnan, A; Knezevic, K; Evans, K; Richards, LA; Lee, E; Morris, J; Goldberg, L; Izraeli, S; Wong, JWH; Olivier, J; Lock, RB; MacKenzie, KL; Pimanda, JE
2016-12-01A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional networkUnnikrishnan, A; Guan, YF; Huang, Y; Beck, D; Thoms, JAI; Peirs, S; Knezevic, K; Ma, S; De Walle, IV; De Jong, IDE; Ali, Z; Zhong, L; Raftery, MJ; Taghon, T; Larsson, J; MacKenzie, KL; Van Vlierberghe, P; Wong, JWH; Pimanda, JE
2020-08The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1.Carmichael, CL; Wang, J; Nguyen, T; Kolawole, O; Benyoucef, A; De Mazière, C; Milne, AR; Samuel, S; Gillinder, K; Hediyeh-Zadeh, S; Vo, ANQ; Huang, Y; Knezevic, K; McInnes, WRL; Shields, BJ; Mitchell, H; Ritchie, ME; Lammens, T; Lintermans, B; Van Vlierberghe, P; Wong, NC; Haigh, K; Thoms, JAI; Toulmin, E; Curtis, DJ; Oxley, EP; Dickins, RA; Beck, D; Perkins, A; McCormack, MP; Davis, MJ; Berx, G; Zuber, J; Pimanda, JE; Kile, BT; Goossens, S; Haigh, JJ
2019-12-01Transcriptional networks in acute myeloid leukemiaThoms, JAI; Beck, D; Pimanda, JE