TY - JOUR AB - Copyright © 2017 John Wiley & Sons, Ltd. Objective: Female partners of men with prostate cancer (PCa) experience heightened psychological distress; however, long-term distress for this group is not well described. We examined partner's psychological and cancer-specific distress over 2 years and predictors of change. Methods: A cohort of 427 female partners (63% response; mean age 62.6 y) of PCa survivors completed baseline (2-4 y post-PCa treatment) assessments of anxiety, depression, and cancer-specific distress and were followed up at 6, 12, 18, and 24 months. Caregiver burden, threat and challenge appraisal, self-efficacy, and dyadic adjustment were assessed as potential predictors of distress. Results: Over time, 23% to 25% of women reported anxiety; 8% to 11% depression; 5% to 6% high cancer-specific distress. Higher caregiver burden and more threat appraisals were associated with increased distress, anxiety, depression, and cancer-specific distress over time. Higher dyadic adjustment over time and more challenge appraisals at 24 months were associated with less distress, anxiety, and depression. Increased partner self-efficacy was associated with lower distress and depression at baseline. Conclusions: A substantial subgroup of partners experience ongoing anxiety, with depression less prevalent but also persistent. Caregiver burden, partner self-efficacy, threat, and challenge appraisals present as potential supportive care targets. AU - Hyde, MK AU - Legg, M AU - Occhipinti, S AU - Lepore, SJ AU - Ugalde, A AU - Zajdlewicz, L AU - Laurie, K AU - Dunn, J AU - Chambers, SK DA - 2018/03/01 DO - 10.1002/pon.4617 EP - 954 JO - Psycho-Oncology PY - 2018/03/01 SP - 946 TI - Predictors of long-term distress in female partners of men diagnosed with prostate cancer VL - 27 Y1 - 2018/03/01 Y2 - 2026/06/12 ER -