TY  - JOUR
AB  - Pseudomonas fluorescens Pf-5 is a plant commensal bacterium that inhabits the rhizosphere and produces secondary metabolites that suppress soilborne plant pathogens. The complete sequence of the 7.1-Mb Pf-5 genome was determined. We analyzed repeat sequences to identify genomic islands that, together with other approaches, suggested P. fluorescens Pf-5's recent lateral acquisitions include six secondary metabolite gene clusters, seven phage regions and a mobile genomic island. We identified various features that contribute to its commensal lifestyle on plants, including broad catabolic and transport capabilities for utilizing plant-derived compounds, the apparent ability to use a diversity of iron siderophores, detoxification systems to protect from oxidative stress, and the lack of a type III secretion system and toxins found in related pathogens. In addition to six known secondary metabolites produced by P. fluorescens Pf-5, three novel secondary metabolite biosynthesis gene clusters were also identified that may contribute to the biocontrol properties of P. fluorescens Pf-5.
AU  - Paulsen, IT
AU  - Press, CM
AU  - Ravel, J
AU  - Kobayashi, DY
AU  - Myers, GSA
AU  - Mavrodi, DV
AU  - DeBoy, RT
AU  - Seshadri, R
AU  - Ren, Q
AU  - Madupu, R
AU  - Dodson, RJ
AU  - Durkin, AS
AU  - Brinkac, LM
AU  - Daugherty, SC
AU  - Sullivan, SA
AU  - Rosovitz, MJ
AU  - Gwinn, ML
AU  - Zhou, L
AU  - Schneider, DJ
AU  - Cartinhour, SW
AU  - Nelson, WC
AU  - Weidman, J
AU  - Watkins, K
AU  - Tran, K
AU  - Khouri, H
AU  - Pierson, EA
AU  - Pierson, LS
AU  - Thomashow, LS
AU  - Loper, JE
DA  - 2005/12/01
DO  - 10.1038/nbt1110
EP  - 878
JO  - Nature Biotechnology
PY  - 2005/12/01
SP  - 873
TI  - Complete genome sequence of the plant commensal Pseudomonas fluorescens Pf-5
VL  - 23
Y1  - 2005/12/01
Y2  - 2026/06/08
ER  -