TY  - JOUR
AB  - A new pentacyclic Stemona alkaloid, stemocurtisinol (3), with a pyrido[1,2-?]azepine A,B-ring system, and the known pyrrolo[1,2-? ]azepine alkaloid oxyprotostemonine (4) have been isolated from a root extract of S. curtisii. The structure and relative stereochemistry of stemocurtisinol was determined by spectral data interpretation and X-ray crystallography. This compound is a diastereoisomer of oxystemokerrin and has the opposite configuration at C-4 and C-19. The individual alkaloid components showed significant larvicidal activity (IC50 4-39 ppm) on mosquito larvae (Anopheles minimus HO).
AU  - Mungkornasawakul, P
AU  - Pyne, SG
AU  - Jatisatienr, A
AU  - Supyen, D
AU  - Jatisatienr, C
AU  - Lie, W
AU  - Ung, AT
AU  - Skelton, BW
AU  - White, AH
DA  - 2004/04/01
DO  - 10.1021/np034066u
EP  - 677
JO  - Journal of Natural Products
PY  - 2004/04/01
SP  - 675
TI  - Phytochemical and Larvicidal Studies on Stemona curtisii: Structure of a New Pyrido[1,2-a]azepine Stemona Alkaloid
VL  - 67
Y1  - 2004/04/01
Y2  - 2026/07/03
ER  -