http://hdl.handle.net/10453/35219 2026-04-29T14:54:35Z http://hdl.handle.net/10453/194791 Title: Examining Carbon Tax Feasibility in Malaysia: Anticipated Adverse Effects and Public Acceptance Authors: Guglyuvatyy, E Abstract: This article discusses the potential implementation of a carbon tax in Malaysia. It examines the expected adverse effects of implementing such a policy, particularly focusing on the projected increase in electricity and fuel costs, which could affect both businesses and households. The main argument presented here is that a judiciously designed carbon tax policy, accompanied by a public information campaign explaining the allocation of revenues aimed at alleviating the impacts of escalating energy and fuel costs for low-income taxpayers and businesses has the potential to increase the acceptance of a carbon tax among Malaysian public and business. This, in turn, can help Malaysia move towards a sustainable and resilient future, where environmental considerations and economic growth are in harmony. 2024-01-01T00:00:00Z http://hdl.handle.net/10453/194726 Title: Women and Housing After the Lismore Floods (Australia)-A Relational Rights-Based Approach Authors: Ewenson, L Abstract: Australia is experiencing both a housing crisis and an increase in extreme weather events due to global warming. This largely dry continent, beset by bushfires and floods, is a land of stark inequality. These inequitable landscapes make recovery from disaster difficult and prolonged for those already marginalised. National statistics reveal that older women are the fastest growing group facing housing precarity, and disasters compound upon this dire situation. This paper presents a relational rights-based approach, informed by a feminist ethics of care, to attain the right to adequate housing for all in the Australian context. 2025-08-01T00:00:00Z http://hdl.handle.net/10453/194642 Title: A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis. Authors: Qian, J; Ma, C; Waterbury, QT; Zhi, X; Moon, CS; Tu, R; Kobayashi, H; Wu, F; Zheng, B; Zeng, Y; Zheng, H; Ochiai, Y; White, RA; Harle, DW; LaBella, JS; Zamechek, LB; ZhongMing Hu, L; Moy, RH; Han, AS; Daugherty, BL; Lederman, S; Wang, TC Abstract: Pathologically activated immunosuppressive neutrophils impair cancer immunotherapy efficacy. The chemokine receptor CXCR4, a central regulator of hematopoiesis and neutrophil biology, represents an attractive target. Here, we fuse a secreted CXCR4 partial agonist, trefoil factor 2 (TFF2), to mouse serum albumin (MSA) and demonstrate that TFF2-MSA peptide synergizes with anti-PD-1 to inhibit primary tumor growth and distant metastases and prolongs survival in gastric cancer (GC) mouse models. Using histidine decarboxylase (Hdc)-GFP transgenic mice to track polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC) in vivo, we find that TFF2-MSA selectively reduces the Hdc-GFP+CXCR4high immunosuppressive neutrophils, thereby boosting CD8+ T cell-mediated tumor killing with anti-PD-1. Importantly, TFF2-MSA reduces bone marrow granulopoiesis, contrasting with CXCR4 antagonism, which fails to confer therapeutic benefits. In GC patients, elevated CXCR4+LOX-1+ low-density neutrophils correlate with lower circulating TFF2 levels. Collectively, our studies introduce a strategy that utilizes CXCR4 partial agonism to restore anti-PD-1 sensitivity by targeting immunosuppressive neutrophils and granulopoiesis. 2025-08-11T00:00:00Z http://hdl.handle.net/10453/193538 Title: He, her, they robot: gendered AI chatbots and the proliferation of technologically facilitated violence Authors: Hook, S; Sassine, J