Adult stem cell coatings for regenerative medicine

Green, DW; Li, G; Milthorpe, B; Ben-Nissan, B

Adult stem cell coatings for regenerative medicine

Green, DW Li, G Milthorpe, B

Ben-Nissan, B

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Publication Type:: Journal Article
Citation:: Materials Today, 2012, 15 (1-2), pp. 60 - 66
Issue Date:: 2012-01-01

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Field	Value	Language
dc.contributor.author	Green, DW	en_US
dc.contributor.author	Li, G	en_US
dc.contributor.author	Milthorpe, B https://orcid.org/0000-0002-0867-9586	en_US
dc.contributor.author	Ben-Nissan, B	en_US
dc.date.issued	2012-01-01	en_US
dc.identifier.citation	Materials Today, 2012, 15 (1-2), pp. 60 - 66	en_US
dc.identifier.issn	1369-7021	en_US
dc.identifier.uri	http://hdl.handle.net/10453/18698
dc.description.abstract	Stem cells can become potent tools for the treatment of degenerative disorders such as heart failure, eye disease and osteoarthritis. Housing stem cells inside a hydrogel coating, directly deposited around them individually and in groups, may be an important solution to the problem of increasing stem cell viability and protection in cultivation. Such coatings can target regulatory proteins and genes for maintenance, differentiation and development into tissues. Already polymer coatings are being applied directly to protect insulin producing pancreatic islet cells in the hope of treating type I diabetes. Here, we review current emerging developments in adult mesenchymal stem cell nanocoating and microcoating techniques and assess their unique practical engineering, biological and potential clinical advantages. © 2012 Elsevier Ltd.	en_US
dc.relation.ispartof	Materials Today	en_US
dc.relation.isbasedon	10.1016/S1369-7021(12)70021-4	en_US
dc.subject.classification	Materials	en_US
dc.title	Adult stem cell coatings for regenerative medicine	en_US
dc.type	Journal Article
utslib.citation.volume	1-2	en_US
utslib.citation.volume	15	en_US
utslib.for	0304 Medicinal and Biomolecular Chemistry	en_US
utslib.for	03 Chemical Sciences	en_US
utslib.for	09 Engineering	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
utslib.copyright.status	closed_access
pubs.issue	1-2	en_US
pubs.publication-status	Published	en_US
pubs.volume	15	en_US

Abstract:

Stem cells can become potent tools for the treatment of degenerative disorders such as heart failure, eye disease and osteoarthritis. Housing stem cells inside a hydrogel coating, directly deposited around them individually and in groups, may be an important solution to the problem of increasing stem cell viability and protection in cultivation. Such coatings can target regulatory proteins and genes for maintenance, differentiation and development into tissues. Already polymer coatings are being applied directly to protect insulin producing pancreatic islet cells in the hope of treating type I diabetes. Here, we review current emerging developments in adult mesenchymal stem cell nanocoating and microcoating techniques and assess their unique practical engineering, biological and potential clinical advantages. © 2012 Elsevier Ltd.

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http://hdl.handle.net/10453/18698