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Issue DateTitleAuthor(s)
2018-02-01A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patientsBeck, D; Thoms, JAI; Palu, C; Herold, T; Shah, A; Olivier, J; Boelen, L; Huang, Y; Chacon, D; Brown, A; Babic, M; Hahn, C; Perugini, M; Zhou, X; Huntly, BJ; Schwarzer, A; Klusmann, JH; Berdel, WE; Wörmann, B; Büchner, T; Hiddemann, W; Bohlander, SK; To, LB; Scott, HS; Lewis, ID; D'Andrea, RJ; Wong, JWH; Pimanda, JE
2015-04-15Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemiasTursky, ML; Beck, D; Thoms, JAI; Huang, Y; Kumari, A; Unnikrishnan, A; Knezevic, K; Evans, K; Richards, LA; Lee, E; Morris, J; Goldberg, L; Izraeli, S; Wong, JWH; Olivier, J; Lock, RB; MacKenzie, KL; Pimanda, JE
2016-07-01MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferationHuang, Y; Thoms, JAI; Tursky, ML; Knezevic, K; Beck, D; Chandrakanthan, V; Suryani, S; Olivier, J; Boulton, A; Glaros, EN; Thomas, SR; Lock, RB; MacKenzie, KL; Bushweller, JH; Wong, JWH; Pimanda, JE
2019-12-01Transcriptional networks in acute myeloid leukemiaThoms, JAI; Beck, D; Pimanda, JE
2020-12Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia.Dun, MD; Mannan, A; Rigby, CJ; Butler, S; Toop, HD; Beck, D; Connerty, P; Sillar, J; Kahl, RGS; Duchatel, RJ; Germon, Z; Faulkner, S; Chi, M; Skerrett-Byrne, D; Murray, HC; Flanagan, H; Almazi, JG; Hondermarck, H; Nixon, B; De Iuliis, G; Chamberlain, J; Alvaro, F; de Bock, CE; Morris, JC; Enjeti, AK; Verrills, NM
2013-01-01Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemiaDiffner, E; Beck, D; Gudgin, E; Thoms, JAI; Knezevic, K; Pridans, C; Foster, S; Goode, D; Lim, WK; Boelen, L; Metzeler, KH; Micklem, G; Bohlander, SK; Buske, C; Burnett, A; Ottersbach, K; Vassiliou, GS; Olivier, J; Wong, JWH; Göttgens, B; Huntly, BJ; Pimanda, JE
2021-06-01Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells.Thoms, JAI; Truong, P; Subramanian, S; Knezevic, K; Harvey, G; Huang, Y; Seneviratne, JA; Carter, DR; Joshi, S; Skhinas, J; Chacon, D; Shah, A; de Jong, I; Beck, D; Gottgens, B; Larsson, J; Wong, JWH; Zanini, F; Pimanda, JE
2016-12-01A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional networkUnnikrishnan, A; Guan, YF; Huang, Y; Beck, D; Thoms, JAI; Peirs, S; Knezevic, K; Ma, S; De Walle, IV; De Jong, IDE; Ali, Z; Zhong, L; Raftery, MJ; Taghon, T; Larsson, J; MacKenzie, KL; Van Vlierberghe, P; Wong, JWH; Pimanda, JE
2013-10-10Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemiaGoldberg, L; Tijssen, MR; Birger, Y; Hannah, RL; Kinston, SJ; Schütte, J; Beck, D; Knezevic, K; Schiby, G; Jacob-Hirsch, J; Biran, A; Kloog, Y; Marcucci, G; Bloomfield, CD; Aplan, PD; Pimanda, JE; Göttgens, B; Izraeli, S
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