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Issue DateTitleAuthor(s)
2007-11-29Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compoundsSkinner-Adams, TS; Lowther, J; Teuscher, F; Stack, CM; Grembecka, J; Mucha, A; Kafarski, P; Trenholme, KR; Dalton, JP; Gardiner, DL
2017-03-01Comparative proteomic analysis of two pathogenic Tritrichomonas foetus genotypes: there is more to the proteome than meets the eyeStroud, LJ; Šlapeta, J; Padula, MP; Druery, D; Tsiotsioras, G; Coorssen, JR; Stack, CM
2007-01-19Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase: A protease involved in amino acid regulation with potential for antimalarial drug developmentStack, CM; Lowther, J; Cunningham, E; Donnelly, S; Gardiner, DL; Trenholme, KR; Skinner-Adams, TS; Teuscher, F; Grembecka, J; Mucha, A; Kafarski, P; Lua, L; Bell, A; Dalton, JP
2004-04-23Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: Propeptide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cellsCollins, PR; Stack, CM; O'Neill, SM; Doyle, S; Ryan, T; Brennan, GP; Mousley, A; Stewart, M; Maule, AG; Dalton, JP; Donnelly, S
2007-06-01The major secreted cathepsin L1 protease of the liver fluke, Fasciola hepatica: A Leu<sup>-12</sup> to Pro<sup>-12</sup> replacement in the nonconserved C-terminal region of the prosegment prevents complete enzyme autoactivation and allows definition of the molecular events in prosegment removalStack, CM; Donnelly, S; Lowther, J; Xu, W; Collins, PR; Brinen, LS; Dalton, JP
2005-09-01De-glycosylation of Pichia pastoris-produced Schistosoma mansoni cathepsin B eliminates non-specific reactivity with IgG in normal human serumStack, CM; Dalton, JP; Cunneen, M; Donnelly, S
2007-10-19The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparumTeuscher, F; Lowther, J; Skinner-Adams, TS; Spielmann, T; Dixon, MWA; Stack, CM; Donnelly, S; Mucha, A; Kafarski, P; Vassiliou, S; Gardiner, DL; Dalton, JP; Trenholme, KR
2006-09-18Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepaticaSekiya, M; Mulcahy, G; Irwin, JA; Stack, CM; Donnelly, SM; Xu, W; Collins, P; Dalton, JP
2008-04-11Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepaticaStack, CM; Caffrey, CR; Donnelly, SM; Seshaadri, A; Lowther, J; Tort, JF; Collins, PR; Robinson, MW; Xu, W; McKerrow, JH; Craik, CS; Geiger, SR; Marion, R; Brinen, LS; Dalton, JP
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