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Issue DateTitleAuthor(s)
2013-12-01Proteolytic activation of Chlamydia trachomatis HTRA is mediated by PDZ1 domain interactions with protease domain loops L3 and LC and beta strand β5Marsh, JW; Lott, WB; Tyndall, JDA; Huston, WWM
2018-03-22Stereochemical basis for the anti-chlamydial activity of the phosphonate protease inhibitor JO146Agbowuro, AA; Mazraani, R; McCaughey, LC; Huston, WM; Gamble, AB; Tyndall, JDA
2012-04-01The active site residue V266 of chlamydial HtrA is critical for substrate binding during both in vitro and in vivo conditionsGloeckl, S; Tyndall, JDA; Stansfield, SH; Timms, P; Huston, WM
2016-08-17Chlamydia Serine Protease Inhibitor, targeting HtrA, as a New Treatment for Koala Chlamydia infectionLawrence, A; Fraser, T; Gillett, A; Tyndall, JDA; Timms, P; Polkinghorne, A; Huston, WM
2013-08-01Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatisGloeckl, S; Ong, VA; Patel, P; Tyndall, JDA; Timms, P; Beagley, KW; Allan, JA; Armitage, CW; Turnbull, L; Whitchurch, CB; Merdanovic, M; Ehrmann, M; Powers, JC; Oleksyszyn, J; Verdoes, M; Bogyo, M; Huston, WM
2011-09-08Unique residues involved in activation of the multitasking protease/chaperone HtrA from Chlamydia trachomatisHuston, WM; Tyndall, JDA; Lott, WB; Stansfield, SH; Timms, P
2015-09-30A Chlamydia trachomatis strain with a chemically generated amino acid substitution (P370L) in the cthtrA gene shows reduced elementary body production Microbial genetics, genomics and proteomicsMarsh, JW; Wee, BA; Tyndall, JDA; Lott, WB; Bastidas, RJ; Caldwell, HD; Valdivia, RH; Kari, L; Huston, WM
2017-07-01CtHtrA: The lynchpin of the chlamydial surface and a promising therapeutic targetMarsh, JW; Ong, VA; Lott, WB; Timms, P; Tyndall, JDA; Huston, WM
2019-09-15Structure-activity analysis of peptidic Chlamydia HtrA inhibitorsAgbowuro, AA; Hwang, J; Peel, E; Mazraani, R; Springwald, A; Marsh, JW; McCaughey, L; Gamble, AB; Huston, WM; Tyndall, JDA
2018-07-01Proteases and protease inhibitors in infectious diseasesAgbowuro, AA; Huston, WM; Gamble, AB; Tyndall, JDA
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