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Issue DateTitleAuthor(s)
2014-01-01Identification of potent and selective inhibitors of the plasmodium falciparum M18 aspartyl aminopeptidase (PfM18AAP) of human malaria via high-throughput screeningSpicer, T; Fernandez-Vega, V; Chase, P; Scampavia, L; To, J; Dalton, JP; Da Silva, FL; Skinner-Adams, TS; Gardiner, DL; Trenholme, KR; Brown, CL; Ghosh, P; Porubsky, P; Wang, JL; Whipple, DA; Schoenen, FJ; Hodder, P
2016-10-01A Plasmodium falciparum S33 proline aminopeptidase is associated with changes in erythrocyte deformabilityda Silva, FL; Dixon, MWA; Stack, CM; Teuscher, F; Taran, E; Jones, MK; Lovas, E; Tilley, L; Brown, CL; Trenholme, KR; Dalton, JP; Gardiner, DL; Skinner-Adams, TS
2010-02-09Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidasesMcGowan, S; Oellig, CA; Birru, WA; Caradoc-Davies, TT; Stack, CM; Lowther, J; Skinner-Adams, T; Mucha, A; Kafarski, P; Grembecka, J; Trenholme, KR; Buckle, AM; Gardiner, DL; Dalton, JP; Whisstock, JC
2012-09-28X-ray crystal structure and specificity of the plasmodium falciparum malaria aminopeptidase PfM18AAPSivaraman, KK; Oellig, CA; Huynh, K; Atkinson, SC; Poreba, M; Perugini, MA; Trenholme, KR; Gardiner, DL; Salvesen, G; Drag, M; Dalton, JP; Whisstock, JC; McGowan, S
2012-06-01The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malariaSkinner-Adams, TS; Peatey, CL; Anderson, K; Trenholme, KR; Krige, D; Brown, CL; Stack, C; Nsangou, DMM; Mathews, RT; Thivierge, K; Dalton, JP; Gardiner, DL
2010-06-25Aminopeptidases of malaria parasites: New targets for chemotherapyTrenholme, KR; Brown, CL; Skinner-Adams, TS; Stack, C; Lowther, J; To, J; Robinson, MW; Donnelly, SM; Dalton, JP; Gardiner, DL
2017-12-01N-terminomics identifies widespread endoproteolysis and novel methionine excision in a genome-reduced bacterial pathogenBerry, IJ; Jarocki, VM; Tacchi, JL; Raymond, BBA; Widjaja, M; Padula, MP; Djordjevic, SP
2014-06-06Cilium Adhesin P216 (MHJ-0493) is a target of ectodomain shedding and aminopeptidase activity on the surface of mycoplasma hyopneumoniaeTacchi, JL; Raymond, BBA; Jarocki, VM; Berry, IJ; Padula, MP; Djordjevic, SP
2012-02-16Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparumPoreba, M; McGowan, S; Skinner-Adams, TS; Trenholme, KR; Gardiner, DL; Whisstock, JC; To, J; Salvesen, GS; Dalton, JP; Drag, M
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