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Issue DateTitleAuthor(s)
2013-01-01Dissecting the Active Site of the Collagenolytic Cathepsin L3 Protease of the Invasive Stage of Fasciola hepaticaCorvo, I; O'Donoghue, AJ; Pastro, L; Pi-Denis, N; Eroy-Reveles, A; Roche, L; McKerrow, JH; Dalton, JP; Craik, CS; Caffrey, CR; Tort, JF
2014-01-01Identification of potent and selective inhibitors of the plasmodium falciparum M18 aspartyl aminopeptidase (PfM18AAP) of human malaria via high-throughput screeningSpicer, T; Fernandez-Vega, V; Chase, P; Scampavia, L; To, J; Dalton, JP; Da Silva, FL; Skinner-Adams, TS; Gardiner, DL; Trenholme, KR; Brown, CL; Ghosh, P; Porubsky, P; Wang, JL; Whipple, DA; Schoenen, FJ; Hodder, P
2011-04-01Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, fasciola hepaticaRobinson, MW; Corvo, I; Jones, PM; George, AM; Padula, MP; To, J; Cancela, M; Rinaldi, G; Tort, JF; Roche, L; Dalton, JP
2013-12-01Proteolytic activation of Chlamydia trachomatis HTRA is mediated by PDZ1 domain interactions with protease domain loops L3 and LC and beta strand β5Marsh, JW; Lott, WB; Tyndall, JDA; Huston, WWM
2009-02-24Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidaseMcGowan, S; Porter, CJ; Lowther, J; Stack, CM; Golding, SJ; Skinner-Adams, TS; Trenholme, KR; Teuscher, F; Donnelly, SM; Grembecka, J; Mucha, A; Kafarski, P; Degori, R; Buckle, AM; Gardiner, DL; Whisstock, JC; Dalton, JP
2009-06-16The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: Importance of active site metal ions in the binding of substrates and inhibitorsMaric, S; Donnelly, SM; Robinson, MW; Skinner-Adams, T; Trenholme, KR; Gardiner, DL; Dalton, JP; Stack, CM; Lowther, J
2010-02-09Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidasesMcGowan, S; Oellig, CA; Birru, WA; Caradoc-Davies, TT; Stack, CM; Lowther, J; Skinner-Adams, T; Mucha, A; Kafarski, P; Grembecka, J; Trenholme, KR; Buckle, AM; Gardiner, DL; Dalton, JP; Whisstock, JC
2008-12-01Helminth pathogen cathepsin proteases: it's a family affairRobinson, MW; Dalton, JP; Donnelly, S
2003-05-01Assessment of proteasome activity in cell lysates and tissue homogenates using peptide substratesRodgers, KJ; Dean, RT
2007-09-04Role of conserved active site residues in catalysis by phospholipase B1 from Cryptococcus neoformansJones, PM; Turner, KM; Djordjevic, JT; Sorrell, TC; Wright, LC; George, AM
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