Activated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healing

Blackwell Publishing
Publication Type:
Journal Article
Wound Repair And Regeneration, 2005, 13 (3), pp. 284 - 294
Issue Date:
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Activated protein C (APC) is a serine protease that plays a central role in physiological anticoagulation, and has more recently been shown to be a potent anti-inflammatory mediator. Using cultured human cells, we show here that APC up-regulates the angi
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