Human osteoclasts behaviour on sol-gel derived carbonate hydroxyapatite coatings on anodized titanium alloy substrates

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Show simple item record Ramaswamy, W Ben-Nissan, B Roest, R Haynes, D Zreiqat, H 2009-08-20T13:02:28Z 2006
dc.identifier.citation Key Engineering Materials, 2006, 309-311 I pp. 709 - 712
dc.identifier.issn 1013-9826
dc.identifier.other C1 en_US
dc.description.abstract Titanium alloy has been used as a material for orthopaedic implants, however drawbacks still exist. Considerable efforts have been taken to modify the surface structure of the implant material and improve the biological performance. Previously we have demonstrated that biomaterials surface modification has a significant effect on the regulation of osteogenesis. We have investigated the behaviour of human osteoclasts on sol-gel coated carbonated hydroxyapatite on anodized titanium alloy. Osteoclasts cultured on the modified surface were able to attach and spread, exhibiting the characteristic peripheral brush border. Successful differentiation of the monocytes into osteoclasts and their attachment to the coated surface and the formation of resorption-like imprints indicated that carbonate hydroxyapatite (CHAP) coated titanium alloy play a significant role in regulating the functional activity of osteoclasts.
dc.language eng
dc.title Human osteoclasts behaviour on sol-gel derived carbonate hydroxyapatite coatings on anodized titanium alloy substrates
dc.type Journal Article
dc.parent Key Engineering Materials
dc.journal.volume 309-311 I
dc.journal.number en_US
dc.journal.number 1 en_US
dc.publocation Zurich-Uetikon, Switzerland en_US
dc.identifier.startpage 709 en_US
dc.identifier.endpage 712 en_US SCI.Chemistry and Forensic Sciences en_US
dc.conference Verified OK en_US
dc.for 0999 Other Engineering
dc.personcode 101355
dc.personcode 760028
dc.percentage 100 en_US Other Engineering en_US
dc.classification.type FOR-08 en_US
dc.description.keywords Cell attachment
dc.description.keywords Cell attachment
dc.description.keywords Hydroxyapatite
dc.description.keywords Hydroxyapatite
dc.description.keywords Osteoclasts
dc.description.keywords Osteoclasts
dc.description.keywords Resorption
dc.description.keywords Resorption
dc.description.keywords Sol-Gel
dc.description.keywords Sol-Gel
dc.description.keywords Surface Modifications
dc.description.keywords Surface Modifications
dc.description.keywords Titanium alloy
dc.description.keywords Titanium alloy
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
pubs.organisational-group /University of Technology Sydney/Strength - Health Technologies
utslib.copyright.status Closed Access 2015-04-15 12:17:09.805752+10 2015-04-15 12:17:09.805752+10
pubs.consider-herdc true
pubs.consider-herdc true
utslib.collection.history General Collection (ID: 346) [2015-05-15T14:11:38+10:00]
utslib.collection.history Closed (ID: 3)

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