Risk factors for infection with Campylobacter jejuni flaA genotypes

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dc.contributor.author Unicomb, LE
dc.contributor.author O'Reilly, LC
dc.contributor.author Kirk, D
dc.contributor.author Stafford, RJ
dc.contributor.author Smith, HV
dc.contributor.author Becker, NG
dc.contributor.author Patel, MS
dc.contributor.author Gilbert, GL
dc.contributor.author Study Gropu, AC
dc.contributor.author Djordjevic, SP
dc.date.accessioned 2010-06-16T05:02:36Z
dc.date.issued 2008-01
dc.identifier.citation Epidemiology and Infection, 2008, 136 pp. 1480 - 1491
dc.identifier.issn 0950-2688
dc.identifier.other C5 en_US
dc.identifier.uri http://hdl.handle.net/10453/12111
dc.description.abstract We aimed to explore Campylobacter genotype-specific risk factors in Australia. Isolates collected prospectively from cases recruited into a case-control study were genotyped using flaA restriction fragment-length polymorphism typing (flaA genotyping). Exposure information for cases and controls was collected by telephone interview. Risk factors were examined for major flaA genotypes using logistic and multinomial regression. Five flaA genotypes accounted for 325 of 590 (55%) cases flaA-6b (n=129), flaA-6 (n=70), flaA-10 (n=48), flaA-2 (n=43), flaA-131 (n=35). In Australia, infections due to flaA-10 and flaA-2 were found to be significantly associated with eating non-poultry meat (beef and ham, respectively) in both case-control and inter-genotype comparisons. All major genotypes apart from flaA-10 were associated with chicken consumption in the case-control comparisons. Based on several clinical criteria, infections due to flaA-2 were more severe than those due to other genotypes. Thus genotype analysis may reveal genotype-specific niches and differences in virulence and transmission routes.
dc.format No Code
dc.publisher Cambridge University Press
dc.relation.isbasedon 10.1017/S0950268807000246
dc.subject NA, Epidemiology
dc.subject NA; Epidemiology
dc.title Risk factors for infection with Campylobacter jejuni flaA genotypes
dc.type Journal Article
dc.parent Epidemiology and Infection
dc.journal.volume 136
dc.journal.number en_US
dc.publocation United Kingdom en_US
dc.identifier.startpage 1480 en_US
dc.identifier.endpage 1491 en_US
dc.cauo.name SCI.Institute for Biotechnology of Infectious Diseases en_US
dc.conference Verified OK en_US
dc.for 111706 Epidemiology
dc.personcode 0000052296 en_US
dc.personcode 0000052337 en_US
dc.personcode 0000052338 en_US
dc.personcode 0000052339 en_US
dc.personcode 0000052340 en_US
dc.personcode 0000052341 en_US
dc.personcode 0000052342 en_US
dc.personcode 0000052343 en_US
dc.personcode 0000052300 en_US
dc.personcode 107126 en_US
dc.percentage 100 en_US
dc.classification.name Epidemiology en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords NA en_US
dc.description.keywords NA
dc.staffid en_US
dc.staffid 107126 en_US
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
pubs.organisational-group /University of Technology Sydney/Strength - i3


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