Application of biomechanics to tissue engineering: A personal view

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dc.contributor.author Milthorpe, BK
dc.date.accessioned 2010-07-15T07:27:19Z
dc.date.issued 2008-06
dc.identifier.citation Journal of Mechanics in Medicine and Biology, 2008, 8 (2), pp. 153 - 160
dc.identifier.issn 0219-5194
dc.identifier.other C1UNSUBMIT en_US
dc.identifier.uri http://hdl.handle.net/10453/12808
dc.description.abstract Cellular biomechanics is an area of study that is receiving more attention as time progresses. The response of cells to their mechanical environment, including biomechanical stimuli, has far-reaching ramifications for the area of tissue engineering, especially for tissues designed to withstand mechanical loading (e.g. bone, cartilage, tendons and ligaments, and arteries). The effects of mechanical stimuli on cells are only recently being examined, and the potential role of mechanical stimuli in tissue engineering is still one that is largely ignored in the design of tissue engineering scaffolds. The relationship of mechanical properties of scaffolds or of mechanical stimuli to cell behavior is complex, but vital to the development of the field. Also, understanding the complex interplay of form and environment on cells involves an increase in our knowledge of how cells react to their total environment including mechanical stimuli and material properties. In order to improve tissue engineering outcomes, a nexus must be developed between the mechanical, biochemical, and biological studies of cellular behavior, in the context of extremely complex systems. © 2008 World Scientific Publishing Company.
dc.language eng
dc.relation.isbasedon 10.1142/S0219519408002590
dc.title Application of biomechanics to tissue engineering: A personal view
dc.type Journal Article
dc.parent Journal of Mechanics in Medicine and Biology
dc.journal.volume 2
dc.journal.volume 8
dc.journal.number 2 en_US
dc.publocation Singapore en_US
dc.identifier.startpage 153 en_US
dc.identifier.endpage 160 en_US
dc.cauo.name SCI.Medical and Molecular Biosciences en_US
dc.conference Verified OK en_US
dc.for 0903 Biomedical Engineering
dc.personcode 105631
dc.percentage 100 en_US
dc.classification.name Biomedical Engineering en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords Cell - Material interactions
dc.description.keywords Cellular biomechanics
dc.description.keywords Tissue engineering
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
pubs.organisational-group /University of Technology Sydney/Strength - Health Technologies
utslib.copyright.status Closed Access
utslib.copyright.date 2015-04-15 12:17:09.805752+10
pubs.consider-herdc false
utslib.collection.history Uncategorised (ID: 363)
utslib.collection.history Closed (ID: 3)


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