Synthesis of 2′-aminoalkyl-1-benzylisoquinoline derivatives and medium sized ring analogues with mu opiod receptor binding activities

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dc.contributor.author Mbere-Nguyen, U
dc.contributor.author Ung, AT
dc.contributor.author Pyne, SG
dc.date.accessioned 2011-02-07T06:18:47Z
dc.date.issued 2010-06-05
dc.identifier.citation Tetrahedron, 2010, 66 (23), pp. 4133 - 4143
dc.identifier.issn 0040-4020
dc.identifier.other C1 en_US
dc.identifier.uri http://hdl.handle.net/10453/13097
dc.description.abstract Novel 2′-aminoalkyl-1-benzylisoquinoline compounds and medium size ring analogues have been prepared using reductive alkylation methods. Four of these analogues were tested for biological activity across 48 different CNS receptors and were showed to have binding activities at the mu opiod receptor. Crown Copyright © 2010.
dc.language eng
dc.relation.hasversion Accepted manuscript version en_US
dc.relation.isbasedon 10.1016/j.tet.2010.03.110
dc.title Synthesis of 2′-aminoalkyl-1-benzylisoquinoline derivatives and medium sized ring analogues with mu opiod receptor binding activities
dc.type Journal Article
dc.description.version Published
dc.parent Tetrahedron
dc.journal.volume 23
dc.journal.volume 66
dc.journal.number 23 en_US
dc.publocation United Kingdom en_US
dc.identifier.startpage 4133 en_US
dc.identifier.endpage 4143 en_US
dc.cauo.name SCI.Chemistry and Forensic Sciences en_US
dc.conference Verified OK en_US
dc.for 0305 Organic Chemistry
dc.personcode 106546
dc.percentage 100 en_US
dc.classification.name Organic Chemistry en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
utslib.copyright.status Open Access
utslib.copyright.date 2015-04-15 12:17:09.805752+10
pubs.consider-herdc true
utslib.collection.history School of Chemistry and Forensic Science (ID: 339)
utslib.collection.history Closed (ID: 3)


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