The first report of ovine cerebral neosporosis and evaluation of Neospora caninum prevalence in sheep in New South Wales

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Show simple item record Bishop, S King, J Windsor, P Reichel, MP Ellis, J Šlapeta, J 2011-02-07T06:21:49Z 2010-05
dc.identifier.citation Veterinary Parasitology, 2010, 170 (1-2), pp. 137 - 142
dc.identifier.issn 0304-4017
dc.identifier.other C1 en_US
dc.description.abstract Presence of Neospora caninum DNA was detected in the brain and spinal cord of an adult Merino sheep suspected of dying with acute non-suppurative meningoencephalitis and mild to moderate non-suppurative myelitis. The most severe neurological lesions were found in the midbrain at the rostral coliculi with moderate to severe multifocal vasculitis and gliosis. As this was the first known occurrence of cerebral disease in sheep in Australia caused by N. caninum, we surveyed sera from five sheep properties in New South Wales (NSW) to obtain information on the likely prevalence of N. caninum infection in NSW sheep flocks. Serology using a commercial indirect enzyme-linked immunosorbent assay (ELISA) revealed no N. caninum antibody-positive sheep (n=184). However an observed prevalence for N. caninum antibodies using a commercially available competitive ELISA was 2.2% (5/232). We conclude that although the diagnosis of fatal ovine cerebral neosporosis is of importance to our surveillance program for transmissible spongiform encephalopathy (TSE) exclusion, sheep in NSW are not commonly infected with N. caninum and this species likely plays only a minor role in the life cycle of this parasite in Australia. © 2010 Elsevier B.V.
dc.language eng
dc.relation.hasversion Accepted manuscript version en_US
dc.relation.isbasedon 10.1016/j.vetpar.2010.01.030
dc.title The first report of ovine cerebral neosporosis and evaluation of Neospora caninum prevalence in sheep in New South Wales
dc.title.alternative Investigating the prevalence of Neospora caninum infection in sheep in New South Wales following suspected ovine cerebral neosporosis en_US
dc.type Journal Article
dc.description.version Published
dc.parent Veterinary Parasitology
dc.journal.volume 1-2
dc.journal.volume 170
dc.journal.number 1-2 en_US
dc.publocation Amsterdam, Netherlands en_US
dc.identifier.startpage 137 en_US
dc.identifier.endpage 142 en_US SCI.Faculty of Science en_US
dc.conference Verified OK en_US
dc.for 070709 Veterinary Pathology
dc.for 070708 Veterinary Parasitology
dc.for 070703 Veterinary Diagnosis and Diagnostics
dc.personcode 105509
dc.personcode 910945
dc.percentage 70 en_US Veterinary Parasitology en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US en_US
dc.location.activity en_US
dc.description.keywords ELISA
dc.description.keywords Epidemiology
dc.description.keywords Fatal neurological disease
dc.description.keywords Neospora caninum
dc.description.keywords Neosporosis
dc.description.keywords PCR
dc.description.keywords Prevalence
dc.description.keywords Sheep
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
pubs.organisational-group /University of Technology Sydney/Strength - i3
utslib.copyright.status Open Access 2015-04-15 12:23:47.074767+10
pubs.consider-herdc true
utslib.collection.history General (ID: 2)
utslib.collection.history School of Medical and Molecular Sciences (ID: 341)
utslib.collection.history School of Medical and Molecular Sciences (ID: 341)

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