Design of endoperoxides with anti-Candida activity

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dc.contributor.author Avery, TD
dc.contributor.author Macreadie, PI
dc.contributor.author Greatrex, BW
dc.contributor.author Robinson, TV
dc.contributor.author Taylor, DK
dc.contributor.author Macreadie, IG
dc.date.accessioned 2012-02-02T05:23:22Z
dc.date.issued 2007-01-01
dc.identifier.citation Bioorganic and Medicinal Chemistry, 2007, 15 (1), pp. 36 - 42
dc.identifier.issn 0968-0896
dc.identifier.other C1UNSUBMIT en_US
dc.identifier.uri http://hdl.handle.net/10453/14638
dc.description.abstract Broad antifungal structure-activity relationships governing epoxy-endoperoxides 2 and 3 and their parent endoperoxides 1 are reported. Their inhibitory activity against Candida albicans in conjunction with hemolytic activity and/or growth inhibition of cultured mammalian cells are reported. This information provided guidance for the further development of endoperoxide and epoxy-endoperoxides as topical antifungal agents. © 2006 Elsevier Ltd. All rights reserved.
dc.language eng
dc.relation.isbasedon 10.1016/j.bmc.2006.10.021
dc.title Design of endoperoxides with anti-Candida activity
dc.type Journal Article
dc.description.version Published
dc.parent Bioorganic and Medicinal Chemistry
dc.journal.volume 1
dc.journal.volume 15
dc.journal.number 1 en_US
dc.publocation United Kingdom en_US
dc.identifier.startpage 36 en_US
dc.identifier.endpage 42 en_US
dc.cauo.name SCI.Environmental Sciences en_US
dc.conference Verified OK en_US
dc.for 1115 Pharmacology and Pharmaceutical Sciences
dc.personcode 108249
dc.percentage 100 en_US
dc.classification.name Medicinal and Biomolecular Chemistry en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords Antifungal
dc.description.keywords Artemisinin
dc.description.keywords Candida
dc.description.keywords Endoperoxide
dc.description.keywords Growth inhibition
dc.description.keywords Hemolytic activity
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
pubs.organisational-group /University of Technology Sydney/Strength - C3
utslib.copyright.status Closed Access
utslib.copyright.date 2015-04-15 12:17:09.805752+10
pubs.consider-herdc false
utslib.collection.history Uncategorised (ID: 363)
utslib.collection.history Closed (ID: 3)


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