Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines

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dc.contributor.author Macreadie, IG
dc.contributor.author Avery, TD
dc.contributor.author Robinson, TV
dc.contributor.author Macreadie, PI
dc.contributor.author Barraclough, M
dc.contributor.author Taylor, DK
dc.contributor.author Tiekink, ER
dc.date.accessioned 2012-02-02T05:39:39Z
dc.date.issued 2008-01
dc.identifier.citation Tetrahedron, 2008, 64 (7), pp. 1225 - 1232
dc.identifier.issn 0040-4020
dc.identifier.other C1UNSUBMIT en_US
dc.identifier.uri http://hdl.handle.net/10453/14670
dc.description.abstract In an ongoing effort to rationally design new antimicrobials, 47 new 1,2-dioxines have been synthesised. Broad antifungal structureactivity relationships governing aromatically substituted epoxy-1,2-dioxines 2 and 3 and their parent 1,2-dioxines 1 were assessed primarily against the pathogenic yeast, Candida albicans, with haemolytic activity of selected examples also reported.
dc.publisher Pergamon
dc.relation.isbasedon 10.1016/j.tet.2007.11.071
dc.title Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines
dc.type Journal Article
dc.parent Tetrahedron
dc.journal.volume 7
dc.journal.volume 64
dc.journal.number 7 en_US
dc.publocation United Kingdom en_US
dc.identifier.startpage 1225 en_US
dc.identifier.endpage 1232 en_US
dc.cauo.name SCI.Environmental Sciences en_US
dc.conference Verified OK en_US
dc.for 0304 Medicinal and Biomolecular Chemistry
dc.personcode 108249
dc.percentage 100 en_US
dc.classification.name Medicinal and Biomolecular Chemistry en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords Antifungal; 1,2-Dioxine; Candida; Epoxy-1,2-dioxine; Haemolytic activity en_US
dc.description.keywords Antifungal
dc.description.keywords Antifungal
dc.description.keywords 1,2-Dioxine
dc.description.keywords 1,2-Dioxine
dc.description.keywords Candida
dc.description.keywords Candida
dc.description.keywords Epoxy-1,2-dioxine
dc.description.keywords Epoxy-1,2-dioxine
dc.description.keywords Haemolytic activity
dc.description.keywords Haemolytic activity
dc.description.keywords Antifungal
dc.description.keywords 1,2-Dioxine
dc.description.keywords Candida
dc.description.keywords Epoxy-1,2-dioxine
dc.description.keywords Haemolytic activity
dc.description.keywords Antifungal
dc.description.keywords 1,2-Dioxine
dc.description.keywords Candida
dc.description.keywords Epoxy-1,2-dioxine
dc.description.keywords Haemolytic activity
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
pubs.organisational-group /University of Technology Sydney/Strength - C3
utslib.copyright.status Closed Access
utslib.copyright.date 2015-04-15 12:17:09.805752+10


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