Amnesic shellfish poisoning toxins in bivalve molluscs in Ireland

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dc.contributor.author James, KJ
dc.contributor.author Gillman, M
dc.contributor.author Amandi, MF
dc.contributor.author López-Rivera, A
dc.contributor.author Puente, PF
dc.contributor.author Lehane, M
dc.contributor.author Mitrovic, S
dc.contributor.author Furey, A
dc.date.accessioned 2012-02-02T11:01:16Z
dc.date.issued 2005-12-15
dc.identifier.citation Toxicon, 2005, 46 (8), pp. 852 - 858
dc.identifier.issn 0041-0101
dc.identifier.other C1UNSUBMIT en_US
dc.identifier.uri http://hdl.handle.net/10453/15627
dc.description.abstract In December 1999, domoic acid (DA) a potent neurotoxin, responsible for the syndrome Amnesic Shellfish Poisoning (ASP) was detected for the first time in shellfish harvested in Ireland. Two liquid chromatography (LC) methods were applied to quantify DA in shellfish after sample clean-up using solid-phase extraction (SPE) with strong anion exchange (SAX) cartridges. Toxin detection was achieved using photodiode array ultraviolet (LC-UV) and multiple tandem mass spectrometry (LC-MSn). DA was identified in four species of bivalve shellfish collected along the west and south coastal regions of the Republic of Ireland. The amount of DA that was present in three species was within EU guideline limits for sale of shellfish (20 μg DA/g); mussels (Mytilus edulis), <1.0 μg DA/g; oysters (Crassostrea edulis), <5.0 μg DA/g and razor clams (Ensis siliqua), <0.3 μg DA/g. However, king scallops (Pecten maximus) posed a significant human health hazard with levels up to 240 μg DA/g total tissues. Most scallop samples (55%) contained DA at levels greater than the regulatory limit. The DA levels in the digestive glands of some samples of scallops were among the highest that have ever been recorded (2820 μg DA/g). © 2005 Elsevier Ltd. All rights reserved.
dc.language eng
dc.relation.isbasedon 10.1016/j.toxicon.2005.02.009
dc.title Amnesic shellfish poisoning toxins in bivalve molluscs in Ireland
dc.type Journal Article
dc.parent Toxicon
dc.journal.volume 8
dc.journal.volume 46
dc.journal.number 8 en_US
dc.publocation Oxford, UK en_US
dc.identifier.startpage 852 en_US
dc.identifier.endpage 858 en_US
dc.cauo.name SCI.Faculty of Science en_US
dc.conference Verified OK en_US
dc.for 0608 Zoology
dc.personcode 944240
dc.percentage 100 en_US
dc.classification.name Zoology en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords ASP
dc.description.keywords Domoic acid
dc.description.keywords Food safety
dc.description.keywords LC-MS
dc.description.keywords Shellfish toxin
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
pubs.organisational-group /University of Technology Sydney/Strength - Environmental Science
utslib.copyright.status Closed Access
utslib.copyright.date 2015-04-15 12:17:09.805752+10
pubs.consider-herdc false
utslib.collection.history School of the Environment (ID: 344)
utslib.collection.history Closed (ID: 3)


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