Quality, interpretation and presentation of European Organisation for Research and Treatment of Cancer quality of life questionnaire core 30 data in randomised controlled trials

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dc.contributor.author Cocks, K
dc.contributor.author King, MT
dc.contributor.author Velikova, G
dc.contributor.author Fayers, P
dc.contributor.author Brown, J
dc.date.accessioned 2012-02-10T06:09:21Z
dc.date.issued 2008-01
dc.identifier.citation European Journal of Cancer, 2008, 44 (13), pp. 1793 - 1798
dc.identifier.issn 0959-8049
dc.identifier.other C1 en_US
dc.identifier.uri http://hdl.handle.net/10453/16999
dc.description.abstract Aim To review reporting standard, presentation and interpretation for quality of life (QOL) outcomes in randomised controlled trials (RCTs) using the European Organisation for Research and Treatment of Cancer quality of life questionnaire core 30 (EORTC QLQ-C30). Methods Cancer RCTs reporting EORTC QLQ-C30 data were identified and reviewed against a reporting quality checklist. Interpretation/presentation methods for QOL data were also recorded. Results Eighty-two papers were reviewed. Seventy percent met criteria for high quality reporting; 94% reported mean scores; 84% presented results in tables/graphs; 80% reported p-values or statistical significance. Clinical significance was addressed in 38%. Where clinical significance was not addressed, reliance was usually on statistical significance to interpret the results. Discussion EORTC QLQ-C30 results are generally reported well, although it was common to rely on statistical significance alone for interpreting results. Whilst interpretation in terms of clinical significance has improved in recent years, there is still a lack of robust clinical interpretation of QOL results even in papers reported to a high standard.
dc.publisher Pergamon
dc.relation.isbasedon 10.1016/j.ejca.2008.05.008
dc.title Quality, interpretation and presentation of European Organisation for Research and Treatment of Cancer quality of life questionnaire core 30 data in randomised controlled trials
dc.type Journal Article
dc.parent European Journal of Cancer
dc.journal.volume 13
dc.journal.volume 44
dc.journal.number 13 en_US
dc.publocation United Kingdom en_US
dc.identifier.startpage 1793 en_US
dc.identifier.endpage 1798 en_US
dc.cauo.name BUS.Centre for Health Economics Research and Evaluation en_US
dc.conference Verified OK en_US
dc.for 1112 Oncology and Carcinogenesis
dc.personcode 020118
dc.percentage 100 en_US
dc.classification.name Oncology and Carcinogenesis en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords Quality of life, QLQ-C30, interpretation en_US
dc.description.keywords Quality of life, QLQ-C30, interpretation
dc.description.keywords Quality of life, QLQ-C30, interpretation
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Business
utslib.copyright.status Closed Access
utslib.copyright.date 2015-04-15 12:17:09.805752+10


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