Kava Anxiety Depression Spectrum Study (KADSS): a mixed methods RCT using an aqueous extract of Piper methysticum.

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dc.contributor.author Sarris, J
dc.contributor.author Kavanagh, DJ
dc.contributor.author Adams, J
dc.contributor.author Bone, K
dc.contributor.author Byrne, G
dc.date.accessioned 2012-02-10T06:09:34Z
dc.date.issued 2009-06
dc.identifier.citation Complementary therapies in medicine, 2009, 17 (3), pp. 176 - 178
dc.identifier.issn 0965-2299
dc.identifier.other C1UNSUBMIT en_US
dc.identifier.uri http://hdl.handle.net/10453/17062
dc.description.abstract OBJECTIVES: To report on the design, significance and potential impacts of the first documented human clinical trial assessing the anxiolytic and thymoleptic efficacy of an aqueous mono-extract of Piper methysticum (kava). The significance of the qualitative element of our clinical trial is also explored. The Kava Anxiety Depression Spectrum Study (KADSS) is a 3-week placebo-controlled, double-blind, cross-over trial involving 60 adult participants (18-65) with elevated stable anxiety and varying levels of depressive symptoms. AIMS: The aims of KADSS are: (1) to determine whether an aqueous standardised extract of kava is effective for the treatment of anxiety; (2) to assess the effects of kava on differing levels of depression; and (3) to explore participants' experience of taking kava via qualitative research. The study also provides preliminary assessment of the safety of an aqueous extract of kava in humans. CONCLUSION: If results reveal that the aqueous kava preparation exerts significant anxiolytic effects and appears safe, potentially beneficial impacts may occur. Data supporting a safe and effective kava extract may encourage a re-introduction of kava to Europe, UK and Canada. This may provide a major socioeconomic benefit to Pacific Island nations, and to sufferers of anxiety disorders.
dc.format Print-Electronic
dc.language eng
dc.relation.isbasedon 10.1016/j.ctim.2009.01.001
dc.title Kava Anxiety Depression Spectrum Study (KADSS): a mixed methods RCT using an aqueous extract of Piper methysticum.
dc.type Journal Article
dc.description.version Published
dc.parent Complementary therapies in medicine
dc.journal.volume 3
dc.journal.volume 17
dc.journal.number 3 en_US
dc.publocation Edinburgh en_US
dc.identifier.startpage 176 en_US
dc.identifier.endpage 178 en_US
dc.cauo.name FOH.Faculty of Health en_US
dc.conference Verified OK en_US
dc.for 1104 Complementary and Alternative Medicine
dc.personcode 112076
dc.percentage 100 en_US
dc.classification.name Complementary and Alternative Medicine en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity ISI:000266422600009 en_US
dc.description.keywords Humans
dc.description.keywords Kava
dc.description.keywords Plant Extracts
dc.description.keywords Phytotherapy
dc.description.keywords Double-Blind Method
dc.description.keywords Anxiety
dc.description.keywords Depression
dc.description.keywords Adolescent
dc.description.keywords Adult
dc.description.keywords Aged
dc.description.keywords Anxiety Disorders
dc.description.keywords Middle Aged
dc.description.keywords Patient Satisfaction
dc.description.keywords Young Adult
dc.description.keywords Anti-Anxiety Agents
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Health
pubs.organisational-group /University of Technology Sydney/Strength - Health Services and Practice Research
utslib.copyright.status Closed Access
utslib.copyright.date 2015-04-15 12:17:09.805752+10
pubs.consider-herdc false
utslib.collection.history Closed (ID: 3)


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