Surgical Adhesion and Its Prevention

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dc.contributor.author Godara, P
dc.contributor.author Milthorpe, BK
dc.contributor.editor Ducheyne, P
dc.contributor.editor Healy, KE
dc.contributor.editor Hutmacher, DW
dc.contributor.editor Grainger, DW
dc.contributor.editor Kirkpatrick, CJ
dc.date.accessioned 2012-10-12T03:37:48Z
dc.date.issued 2011-01
dc.identifier.citation Comprehensive Biomaterials, 2011, 1, pp. 561 - 572
dc.identifier.isbn 978-0-08-055302-3
dc.identifier.other B3 en_US
dc.identifier.uri http://hdl.handle.net/10453/19434
dc.description.abstract Adhesion of freely moving tissues and organs due to surgical injury and trauma can be a serious postoperative complication. High rates of incidence due to surgical intervention, especially associated with abdominal procedures, have been reported. This chapter gives an introduction to the formation of adhesions, with particular focus on peritoneum, urinary and reproductive (female) systems, tendon, ligament, joint, and pericardium. A number of techniques, treatments, and materials have been proposed for the prevention/reduction of adhesion formation. Of these, barrier methods are considered the only effective method currently available. An overview of biomaterials currently used as barriers for postsurgical tissue adhesion is presented. Current clinical practice utilizes solid membranes/mechanical barriers, spray-on, and gel and liquid barriers. These barriers can be either resorbable, nonresorbable, or a combination of both. Complications of barrier films are examined, and design criteria for barrier membranes are presented. Adhesion formation can be beneficial in particular circumstances, such as for anchoring implants, and these uses are commented upon. Much advancement has been made in this area, thanks to the increasing knowledge and understanding regarding the events that control adhesion formation, but there is still a long way to go before an optimum solution to this problem is found.
dc.format Scott McWhirter
dc.publisher Elsevier
dc.relation.isbasedon 10.1016/B978-0-08-055294-1.00244-0
dc.title Surgical Adhesion and Its Prevention
dc.type Chapter
dc.description.version Published
dc.parent Comprehensive Biomaterials
dc.journal.number en_US
dc.publocation USA en_US
dc.identifier.startpage 561 en_US
dc.identifier.endpage 572 en_US
dc.cauo.name SCI.Medical and Molecular Biosciences en_US
dc.conference Verified OK en_US
dc.for 0903 Biomedical Engineering
dc.personcode 105631
dc.personcode 108424
dc.percentage 100 en_US
dc.classification.name Biomedical Engineering en_US
dc.classification.type FOR-08 en_US
dc.edition 1 en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity en_US
dc.description.keywords Abdominal surgery; Adhesion barrier; Adhesion formation; Biocompatibility; Biomaterial; Cardiac surgery; Fibrolysis; Fibrosis; Hyaluronic acid; Resorbable polymers; Sodium carboxymethylcellulose; Tendon surgery; Tissue adhesion en_US
dc.description.keywords Science & Technology
dc.description.keywords Technology
dc.description.keywords Computer Science, Artificial Intelligence
dc.description.keywords Computer Science, Information Systems
dc.description.keywords Computer Science
dc.description.keywords COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE
dc.description.keywords COMPUTER SCIENCE, INFORMATION SYSTEMS
dc.description.keywords context
dc.description.keywords criteria
dc.description.keywords failurelevel
dc.description.keywords time phase
dc.description.keywords time slots
dc.description.keywords trusting agent
dc.description.keywords trusted agent
dc.description.keywords TRUST
dc.description.keywords Abdominal surgery
dc.description.keywords Adhesion barrier
dc.description.keywords Adhesion formation
dc.description.keywords Biocompatibility
dc.description.keywords Biomaterial
dc.description.keywords Cardiac surgery
dc.description.keywords Fibrolysis
dc.description.keywords Fibrosis
dc.description.keywords Hyaluronic acid
dc.description.keywords Resorbable polymers
dc.description.keywords Sodium carboxymethylcellulose
dc.description.keywords Tendon surgery
dc.description.keywords Tissue adhesion
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
pubs.organisational-group /University of Technology Sydney/Strength - Health Technologies
utslib.copyright.status Closed Access
utslib.copyright.date 2015-04-15 12:17:09.805752+10
utslib.collection.history Closed (ID: 3)
utslib.collection.history Uncategorised (ID: 363)


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