Biomarkers of exposure and effect in a lacertid lizard (Podarcis bocagei Seoane) exposed to chlorpyrifos.

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Show simple item record Amaral, MJ Sanchez-Hernandez, JC Bicho, RC Carretero, MA Valente, R Faustino, AM Soares, AM Mann, RM 2014-04-03T01:22:27Z 2012-10
dc.identifier.citation Environmental toxicology and chemistry / SETAC, 2012, 31 (10), pp. 2345 - 2353
dc.identifier.issn 0730-7268
dc.identifier.other C1 en_US
dc.description.abstract In Europe, reptiles have been recently included in environmental risk-assessment processes for registration of plant-protection products. However, data on toxicity effects of most compounds are lacking. Chlorpyrifos is the most commonly used organophosphorus insecticide worldwide. In the present study, the authors exposed a lacertid lizard, Podarcis bocagei, to sublethal concentrations of chlorpyrifos. Individuals were exposed through spiked food for a period of 20 d (low dose 0.12 mg/kg/d, high dose 1.57 mg/kg/d). After exposure, various biomarkers of exposure and effect were evaluated, including the activities of glutathione S-transferase and enzymes involved in the glutathione redox cycle, glutathione concentrations, activities of esterases, liver and testes histopathologies, as well as locomotory and predatory behavior. The results indicate that sublethal, subchronic exposure to chlorpyrifos can affect P. bocagei in a dose-dependent manner. Adverse effects occurred at both the subindividual and individual levels, including inhibition of carboxylesterases and cholinesterases (ChEs), liver histopathological changes, and altered predatory behaviors. Animals exposed to chlorpyrifos took more time to capture and subdue prey items. The results suggest a link between effects at subindividual levels of organization with those observed at the whole individual level after exposure to environmentally realistic dosages of chlorpyrifos.
dc.format Print-Electronic
dc.language eng
dc.relation.isbasedon 10.1002/etc.1955
dc.title Biomarkers of exposure and effect in a lacertid lizard (Podarcis bocagei Seoane) exposed to chlorpyrifos.
dc.type Journal Article
dc.description.version Published
dc.parent Environmental toxicology and chemistry / SETAC
dc.journal.volume 10
dc.journal.volume 31
dc.journal.number 10 en_US
dc.publocation Hoboken en_US
dc.identifier.startpage 2345 en_US
dc.identifier.endpage 2353 en_US SCI.Faculty of Science en_US
dc.conference Verified OK en_US
dc.for 0399 Other Chemical Sciences
dc.personcode 998973
dc.percentage 100 en_US Other Chemical Sciences en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US en_US
dc.location.activity en_US
dc.description.keywords Animals
dc.description.keywords Liver
dc.description.keywords Testis
dc.description.keywords Chlorpyrifos
dc.description.keywords Glutathione Transferase
dc.description.keywords Cholinesterases
dc.description.keywords Glutathione
dc.description.keywords Insecticides
dc.description.keywords Biological Markers
dc.description.keywords Predatory Behavior
dc.description.keywords Lizards
dc.description.keywords Motor Activity
dc.description.keywords Carboxylic Ester Hydrolases
dc.description.keywords Toxicity Tests, Subacute
dc.description.keywords Male
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
utslib.copyright.status Closed Access 2015-04-15 12:17:09.805752+10
pubs.consider-herdc true
utslib.collection.history Closed (ID: 3)

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