Irritable bowel syndrome: A review on the role of intestinal protozoa and the importance of their detection and diagnosis

DSpace/Manakin Repository

Search OPUS

Advanced Search


My Account

Show simple item record Stark, D van Hal, S Marriott, D Ellis, J Harkness, J 2009-12-21T02:30:44Z 2007-01
dc.identifier.citation International Journal for Parasitology, 2007, 37 (1), pp. 11 - 20
dc.identifier.issn 0020-7519
dc.identifier.other C1 en_US
dc.description.abstract Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder in which abdominal pain is associated with a defect or a change in bowel habits. Gut inflammation is one of the proposed mechanisms of pathogenesis. Recent studies have described a possible role for protozoan parasites, such as Blastocystis hominis and Dientamoeba fragilis, in the etiology of IBS. Dientamoeba fragilis is known to cause IBS-like symptoms and has a propensity to cause chronic infections but its diagnosis relies on microscopy of stained smears, which many laboratories do not perform, thereby leading to the misdiagnosis of dientamoebiasis as IBS. The role of B. hominis as an etiological agent of IBS is inconclusive, due to contradictory reports and the controversial nature of B. hominis as a human pathogen. Although Entamoeba histolytica infections occur predominately in developing regions of the world, clinical diagnosis of amebiasis is often difficult because symptoms of patients with IBS may closely mimic those patients with non-dysenteric amoebic colitis. Clinical manifestations of Giardia intestinalis infection also vary from asymptomatic carriage to acute and chronic diarrhoea with abdominal pain. These IBS-like symptoms can be continuous, intermittent, sporadic or recurrent, sometimes lasting years without correct diagnosis. It is essential that all patients with IBS undergo routine parasitological investigations in order to rule out the presence of protozoan parasites as the causative agents of the clinical signs. © 2006 Australian Society for Parasitology Inc.
dc.language eng
dc.relation.isbasedon 10.1016/j.ijpara.2006.09.009
dc.title Irritable bowel syndrome: A review on the role of intestinal protozoa and the importance of their detection and diagnosis
dc.type Journal Article
dc.description.version Published
dc.parent International Journal for Parasitology
dc.journal.volume 1
dc.journal.volume 37
dc.journal.number 1 en_US
dc.publocation Oxford, UK en_US
dc.identifier.startpage 11 en_US
dc.identifier.endpage 20 en_US SCI.Medical and Molecular Biosciences en_US
dc.conference Verified OK en_US
dc.for 0605 Microbiology
dc.personcode 100210
dc.personcode 104964
dc.personcode 100209
dc.personcode 910945
dc.percentage 100 en_US Microbiology en_US
dc.classification.type FOR-08 en_US
dc.description.keywords Blastocystis hominis
dc.description.keywords Dientamoeba fragilis
dc.description.keywords IBS
dc.description.keywords Irritable bowel syndrome
dc.description.keywords Protozoa
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science
pubs.organisational-group /University of Technology Sydney/Strength - i3
utslib.copyright.status Closed Access 2015-04-15 12:17:09.805752+10
pubs.consider-herdc true
utslib.collection.history Closed (ID: 3)
utslib.collection.history School of Medical and Molecular Sciences (ID: 341)

Files in this item

This item appears in the following Collection(s)

Show simple item record