A Novel Family Of Potentially Mobile DNA Elements Encoding Site-Specific Gene-Integration Functions - Integrons

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dc.contributor.author Stokes, H
dc.contributor.author Hall, R
dc.date.accessioned 2010-05-28T09:44:32Z
dc.date.issued 1989-01
dc.identifier.citation Molecular Microbiology, 1989, 3 (12), pp. 1669 - 1683
dc.identifier.issn 0950-382X
dc.identifier.other C1UNSUBMIT en_US
dc.identifier.uri http://hdl.handle.net/10453/8633
dc.description.abstract A family of novel mobile DNA elements is described, examples of which are found at several independent locations and encode a variety of antibiotic resistance genes. The complete elements consist of two conserved segments separated by a segment of variable length and sequence which includes inserted antibiotic resistance genes. The conserved segment located 3' to the inserted resistance genes was sequenced from Tn21 and R46, and the sequences are identical over a region of 2026 bases, which includes the sulphonamide resistance gene sull, and two further open reading frames of unknown function. The complete sequences of both the 3' and 5' conserved regions of the DNA element have been determined. A 59-base sequence element, found at the junctions of inserted DNA sequences and the conserved 3' segment, is also present at this location in the R46 sequence. A copy of one half of this 59-base element is found at the end of the sull gene, suggesting that sull, though part of the conserved region, was also originally inserted into an ancestral element by site-specific integration. Inverted or direct terminal repeats or short target site duplications, both of which are characteristics of class I and class II transposons, are not found at the outer boundaries of the elements described here.
dc.format No Code
dc.publisher Blackwell Science Ltd
dc.relation.isbasedon 10.1111/j.1365-2958.1989.tb00153.x
dc.subject NA, Microbiology
dc.subject NA; Microbiology
dc.title A Novel Family Of Potentially Mobile DNA Elements Encoding Site-Specific Gene-Integration Functions - Integrons
dc.type Journal Article
dc.description.version Published
dc.parent Molecular Microbiology
dc.journal.volume 12
dc.journal.volume 3
dc.journal.number 12 en_US
dc.publocation Oxford en_US
dc.identifier.startpage 1669 en_US
dc.identifier.endpage 1683 en_US
dc.cauo.name SCI.Institute for Biotechnology of Infectious Diseases en_US
dc.conference Verified OK en_US
dc.for 0605 Microbiology
dc.personcode 105741 en_US
dc.personcode 0000023354 en_US
dc.percentage 100 en_US
dc.classification.name Microbiology en_US
dc.classification.type FOR-08 en_US
dc.edition en_US
dc.custom en_US
dc.date.activity en_US
dc.location.activity ISI:A1989CH04400001 en_US
dc.location.activity ISI:A1989CH04400001
dc.description.keywords NA en_US
dc.description.keywords Science & Technology
dc.description.keywords Life Sciences & Biomedicine
dc.description.keywords Ecology
dc.description.keywords Evolutionary Biology
dc.description.keywords Genetics & Heredity
dc.description.keywords Environmental Sciences & Ecology
dc.description.keywords ECOLOGY
dc.description.keywords EVOLUTIONARY BIOLOGY
dc.description.keywords GENETICS & HEREDITY
dc.description.keywords Biogeography
dc.description.keywords Niche conservatism
dc.description.keywords Habitat filtering
dc.description.keywords Phylogenetic clustering
dc.description.keywords Community ecology
dc.description.keywords Mammals
dc.description.keywords Australia
dc.description.keywords COMMUNITY ECOLOGY
dc.description.keywords BODY-SIZE
dc.description.keywords EXTINCTION RISK
dc.description.keywords SPECIES DISTRIBUTION
dc.description.keywords LIMITING SIMILARITY
dc.description.keywords ADAPTIVE RADIATION
dc.description.keywords PLANT-COMMUNITIES
dc.description.keywords LIFE-HISTORIES
dc.description.keywords MODELS
dc.description.keywords CONSERVATION
dc.description.keywords NA
dc.staffid en_US
pubs.embargo.period Not known
pubs.organisational-group /University of Technology Sydney
pubs.organisational-group /University of Technology Sydney/Faculty of Science


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