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Issue DateTitleAuthor(s)
2014-01-01Identification of potent and selective inhibitors of the plasmodium falciparum M18 aspartyl aminopeptidase (PfM18AAP) of human malaria via high-throughput screeningSpicer, T; Fernandez-Vega, V; Chase, P; Scampavia, L; To, J; Dalton, JP; Da Silva, FL; Skinner-Adams, TS; Gardiner, DL; Trenholme, KR; Brown, CL; Ghosh, P; Porubsky, P; Wang, JL; Whipple, DA; Schoenen, FJ; Hodder, P
2016-10-01A Plasmodium falciparum S33 proline aminopeptidase is associated with changes in erythrocyte deformabilityda Silva, FL; Dixon, MWA; Stack, CM; Teuscher, F; Taran, E; Jones, MK; Lovas, E; Tilley, L; Brown, CL; Trenholme, KR; Dalton, JP; Gardiner, DL; Skinner-Adams, TS
2009-02-24Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidaseMcGowan, S; Porter, CJ; Lowther, J; Stack, CM; Golding, SJ; Skinner-Adams, TS; Trenholme, KR; Teuscher, F; Donnelly, SM; Grembecka, J; Mucha, A; Kafarski, P; Degori, R; Buckle, AM; Gardiner, DL; Whisstock, JC; Dalton, JP
2006-01-20Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites: Target for the antimalarial activity of bestatinGardiner, DL; Trenholme, KR; Skinner-Adams, TS; Stack, CM; Dalton, JP
2012-06-25Anti-malaria drug development targeting the M1 alanyl and M17 leucyl aminopeptidasesThivierge, K; Mathew, RT; Nsangou, DMM; Da Silva, F; Cotton, S; Skinner-Adams, TS; Trenholme, KR; Brown, CL; Stack, CM; Gardiner, DL; Dalton, JP
2007-11-29Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compoundsSkinner-Adams, TS; Lowther, J; Teuscher, F; Stack, CM; Grembecka, J; Mucha, A; Kafarski, P; Trenholme, KR; Dalton, JP; Gardiner, DL
2007-10-19The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparumTeuscher, F; Lowther, J; Skinner-Adams, TS; Spielmann, T; Dixon, MWA; Stack, CM; Donnelly, S; Mucha, A; Kafarski, P; Vassiliou, S; Gardiner, DL; Dalton, JP; Trenholme, KR
2012-06-01The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malariaSkinner-Adams, TS; Peatey, CL; Anderson, K; Trenholme, KR; Krige, D; Brown, CL; Stack, C; Nsangou, DMM; Mathews, RT; Thivierge, K; Dalton, JP; Gardiner, DL
2012-02-16Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparumPoreba, M; McGowan, S; Skinner-Adams, TS; Trenholme, KR; Gardiner, DL; Whisstock, JC; To, J; Salvesen, GS; Dalton, JP; Drag, M
2010-06-25Aminopeptidases of malaria parasites: New targets for chemotherapyTrenholme, KR; Brown, CL; Skinner-Adams, TS; Stack, C; Lowther, J; To, J; Robinson, MW; Donnelly, SM; Dalton, JP; Gardiner, DL
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