The pivotal role of impedance in patch clamp technique

Publisher:
IMEDPHARM
Publication Type:
Journal Article
Citation:
Journal of Environment and Life Sciences, 2017, 2 (4), pp. 103 - 109 (6)
Issue Date:
2017-11-23
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Impedance is pivotal when we talk about patch clamp technique which is a unique innovation in the field of knowing channels in vivo and have proved to make a promising difference therapeutically. Many drugs and chemicals are tested for their role in the cell through this channel knowing technique. However the resistance provided during this process is a significantly technical work that determines the success of an experiment. Through this review article we will focus on key impedance roles and effects while performing patch clamp technique and in turn a grip on resistance by the scientist may discover advanced uses of patch clamp instrument using cells such as astrocytes and neurons.
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