Design of endoperoxides with anti-Candida activity

Publication Type:
Journal Article
Bioorganic and Medicinal Chemistry, 2007, 15 (1), pp. 36 - 42
Issue Date:
Filename Description Size
Thumbnail2010001952OK.pdf185.59 kB
Adobe PDF
Full metadata record
Broad antifungal structure-activity relationships governing epoxy-endoperoxides 2 and 3 and their parent endoperoxides 1 are reported. Their inhibitory activity against Candida albicans in conjunction with hemolytic activity and/or growth inhibition of cultured mammalian cells are reported. This information provided guidance for the further development of endoperoxide and epoxy-endoperoxides as topical antifungal agents. © 2006 Elsevier Ltd. All rights reserved.
Please use this identifier to cite or link to this item: