School of Biomedical Engineering

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Test and tune: evaluating, adjusting and optimising the stiffness of hydrogels to influence cell fate

Yang, P Boer, G Snow, F Williamson, A Cheeseman, S Samarasinghe, RM Rifai, A Priyam, A Elnathan, R Guijt, R Quigley, A Kaspa, R Nisbet, DR Williams, RJ

The use of bioequivalent hydrogels in tissue engineering (TE) is enabling 3D tissue-like scaffolds capable of reproducing the sophistication of natural cell–matrix interactions. Alongside the commo...

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Novel accurate classification system developed using order transition pattern feature engineering technique with physiological signals.

Gelen, MA Barua, PD Tasci, I Tasci, G Aydemir, E Dogan, S Tuncer, T Acharya, UR

This paper presents a novel, explainable feature engineering framework for classifying EEG and ECG signals with high accuracy. The proposed method employs the Order Transition Pattern (OTPat) featu...

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AttentionPoolMobileNeXt: An automated construction damage detection model based on a new convolutional neural network and deep feature engineering models

Aydin, M Barua, PD Chadalavada, S Dogan, S Tuncer, T Chakraborty, S Acharya, RU

In 2023, Turkiye faced a series of devastating earthquakes and these earthquakes affected millions of people due to damaged constructions. These earthquakes demonstrated the urgent need for advance...

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Risk-stratified lifetime risk and incidence of hip fracture and falls in middle-aged and elderly Chinese population: The China health and retirement longitudinal study.

Du, G Fan, Z Fan, K Liu, H Zhang, J Li, D Yan, L Jiu, J Li, R Li, X Li, S Jia, L Liu, H Ren, Y Liu, X Li, JJ Wang, B

BACKGROUND: Hip fracture (HF) is one of the most prevalent orthopedic conditions among the elderly, with falls being the primary risk factor for HF. With the surge of aged population, China is faci...

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Cortical Actin Depolymerisation in 3D Cell Culture Enhances Extracellular Vesicle Secretion and Therapeutic Effects.

Yang, Z Li, X Lin, Q Zhou, F Liang, K Li, JJ Niu, Y Meng, Q Zhao, T Li, H Wang, D Lin, J Li, H Wang, B Liu, W Du, Y Lin, J Xing, D

Three-dimensional (3D) culture systems have been shown to enhance cellular secretion of small extracellular vesicles (sEVs) compared to two-dimensional (2D) culture. However, the molecular mechanis...

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MNPDenseNet: Automated Monkeypox Detection Using Multiple Nested Patch Division and Pretrained DenseNet201

Demir, FB Baygin, M Tuncer, I Barua, PD Dogan, S Tuncer, T Ooi, CP Ciaccio, EJ Acharya, UR

Background: Monkeypox is a viral disease caused by the monkeypox virus (MPV). A surge in monkeypox infection has been reported since early May 2022, and the outbreak has been classified as a global...

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Predicting viral host codon fitness and path shifting through tree-based learning on codon usage biases and genomic characteristics.

Su, S Ni, Z Lan, T Ping, P Tang, J Yu, Z Hutvagner, G Li, J

Viral codon fitness (VCF) of the host and the VCF shifting has seldom been studied under quantitative measurements, although they could be concepts vital to understand pathogen epidemiology. This s...

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Mitigating adverse effects of Cu-containing intrauterine devices using a highly biocompatible Cu5Fe alloy.

Yang, L Bao, G Yao, C Diao, T Su, Z Liu, T Li, G Wang, G Chen, X Xu, X Sun, B Xu, X He, B Zheng, Y

Copper-containing intrauterine devices (Cu-IUD) are adopted by worldwide women for contraception with the advantages of long-term effectiveness, reversibility and affordability. However, adverse ef...

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Stress relaxation behavior of the transition zone in the intervertebral disc.

Vieira, L Mordechai, HS Sharabi, M Tipper, JL Tavakoli, J

The stress relaxation of the TZ region, located at the interface of the Annulus Fibrosus (AF) and Nucleus Pulposus (NP) of the disc, and how its stress is relaxed compared to the adjacent regions i...

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Editorial: Emerging bioanalytical techniques and therapies for human disease models.

Wang, X Lu, J Huang, Y Liu, X Fang, G Yang, C-T Guo, Z

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