Targeting MicroRNAs: Promising Future Therapeutics in the Treatment of Allergic Airway Disease.
- Publisher:
- BEGELL HOUSE INC
- Publication Type:
- Journal Article
- Citation:
- Crit Rev Eukaryot Gene Expr, 2018, 28, (2), pp. 125-127
- Issue Date:
- 2018
Closed Access
Filename | Description | Size | |||
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targeting microRNAs- promising future therapeutics in the treatment of allergic airway disease.pdf | Accepted version | 446.43 kB | Adobe PDF |
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Full metadata record
Field | Value | Language |
---|---|---|
dc.contributor.author |
Dua, K https://orcid.org/0000-0002-7507-1159 |
|
dc.contributor.author | Hansbro, NG | |
dc.contributor.author | Foster, PS | |
dc.contributor.author | Hansbro, PM | |
dc.date.accessioned | 2022-03-30T01:02:15Z | |
dc.date.available | 2022-03-30T01:02:15Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Crit Rev Eukaryot Gene Expr, 2018, 28, (2), pp. 125-127 | |
dc.identifier.issn | 1045-4403 | |
dc.identifier.issn | 2162-6502 | |
dc.identifier.uri | http://hdl.handle.net/10453/155694 | |
dc.description.abstract | MicroRNAs (miRNAs) are short noncoding RNAs that control gene expression posttranscriptionally by directly blocking translation of their target mRNAs or by repressing protein production via mRNA destabilization. Investigations into miRNAs began approximately 12 years ago with their discovery in mammalian cells. Still, the involvement of miRNAs in the development of asthma remains unclear, and this topic needs further research to discover various molecular mechanisms responsible for the pathogenesis of asthma and new therapeutic interventions. So far, various miRNAs have been identified in allergic airway disease along with their targets. Our present mini-review highlights the latest information involving the role of miRNAs in asthma. | |
dc.format | ||
dc.language | eng | |
dc.publisher | BEGELL HOUSE INC | |
dc.relation.ispartof | Crit Rev Eukaryot Gene Expr | |
dc.relation.isbasedon | 10.1615/CritRevEukaryotGeneExpr.2018022218 | |
dc.rights | info:eu-repo/semantics/closedAccess | |
dc.subject | 0604 Genetics | |
dc.subject.classification | Biochemistry & Molecular Biology | |
dc.subject.mesh | Asthma | |
dc.subject.mesh | Gene Expression Regulation | |
dc.subject.mesh | Humans | |
dc.subject.mesh | MicroRNAs | |
dc.subject.mesh | RNA, Messenger | |
dc.subject.mesh | Respiratory Hypersensitivity | |
dc.subject.mesh | Respiratory System | |
dc.subject.mesh | Respiratory System | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Asthma | |
dc.subject.mesh | Respiratory Hypersensitivity | |
dc.subject.mesh | MicroRNAs | |
dc.subject.mesh | RNA, Messenger | |
dc.subject.mesh | Gene Expression Regulation | |
dc.title | Targeting MicroRNAs: Promising Future Therapeutics in the Treatment of Allergic Airway Disease. | |
dc.type | Journal Article | |
utslib.citation.volume | 28 | |
utslib.location.activity | United States | |
utslib.for | 1115 Pharmacology and Pharmaceutical Sciences | |
utslib.for | 0604 Genetics | |
pubs.organisational-group | /University of Technology Sydney | |
pubs.organisational-group | /University of Technology Sydney/Faculty of Health | |
pubs.organisational-group | /University of Technology Sydney/Faculty of Science | |
pubs.organisational-group | /University of Technology Sydney/Faculty of Science/School of Life Sciences | |
pubs.organisational-group | /University of Technology Sydney/Faculty of Health/Graduate School of Health | |
pubs.organisational-group | /University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Pharmacy | |
utslib.copyright.status | closed_access | * |
dc.date.updated | 2022-03-30T01:02:13Z | |
pubs.issue | 2 | |
pubs.publication-status | Published | |
pubs.volume | 28 | |
utslib.citation.issue | 2 |
Abstract:
MicroRNAs (miRNAs) are short noncoding RNAs that control gene expression posttranscriptionally by directly blocking translation of their target mRNAs or by repressing protein production via mRNA destabilization. Investigations into miRNAs began approximately 12 years ago with their discovery in mammalian cells. Still, the involvement of miRNAs in the development of asthma remains unclear, and this topic needs further research to discover various molecular mechanisms responsible for the pathogenesis of asthma and new therapeutic interventions. So far, various miRNAs have been identified in allergic airway disease along with their targets. Our present mini-review highlights the latest information involving the role of miRNAs in asthma.
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