Synthesis of alkaloid-like compounds via the bridging Ritter Reaction

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Journal Article
Monatshefte für Chemie, 2012, 143 (6), pp. 955 - 963
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Alkaloid-like compounds containing a benzo[c]azepine core structure were successfully prepared in three steps from H-dibenzo[a,d]cyclohepten-5-ol via the bridging Ritter reaction. Biological studies of these compounds revealed that some of them are AChE inhibitors and antimalarial agents.
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