Vernalization-repression of Arabidopsis FLC requires promoter sequences but not antisense transcripts

Publication Type:
Journal Article
Citation:
PLoS ONE, 2011, 6 (6)
Issue Date:
2011-06-24
Metrics:
Full metadata record
Files in This Item:
Filename Description Size
Thumbnail2012008155OK.pdf344.06 kB
Adobe PDF
The repression of Arabidopsis FLC expression by vernalization (extended cold) has become a model for understanding polycomb-associated epigenetic regulation in plants. Antisense and sense non-coding RNAs have been respectively implicated in initiation and maintenance of FLC repression by vernalization. We show that the promoter and first exon of the FLC gene are sufficient to initiate repression during vernalization; this initial repression of FLC does not require antisense transcription. Long-term maintenance of FLC repression requires additional regions of the gene body, including those encoding sense non-coding transcripts. © 2011 Helliwell et al.
Please use this identifier to cite or link to this item: