Vernalization-repression of Arabidopsis FLC requires promoter sequences but not antisense transcripts

Helliwell, CA; Robertson, M; Finnegan, EJ; Buzas, DM; Dennis, ES

Vernalization-repression of Arabidopsis FLC requires promoter sequences but not antisense transcripts

Helliwell, CA Robertson, M Finnegan, EJ Buzas, DM Dennis, ES

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Publication Type:: Journal Article
Citation:: PLoS ONE, 2011, 6 (6)
Issue Date:: 2011-06-24

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Field	Value	Language
dc.contributor.author	Helliwell, CA	en_US
dc.contributor.author	Robertson, M	en_US
dc.contributor.author	Finnegan, EJ	en_US
dc.contributor.author	Buzas, DM	en_US
dc.contributor.author	Dennis, ES https://orcid.org/0000-0002-7850-591X	en_US
dc.date.available	2011-05-31	en_US
dc.date.issued	2011-06-24	en_US
dc.identifier.citation	PLoS ONE, 2011, 6 (6)	en_US
dc.identifier.uri	http://hdl.handle.net/10453/28754
dc.description.abstract	The repression of Arabidopsis FLC expression by vernalization (extended cold) has become a model for understanding polycomb-associated epigenetic regulation in plants. Antisense and sense non-coding RNAs have been respectively implicated in initiation and maintenance of FLC repression by vernalization. We show that the promoter and first exon of the FLC gene are sufficient to initiate repression during vernalization; this initial repression of FLC does not require antisense transcription. Long-term maintenance of FLC repression requires additional regions of the gene body, including those encoding sense non-coding transcripts. © 2011 Helliwell et al.	en_US
dc.relation.ispartof	PLoS ONE	en_US
dc.relation.isbasedon	10.1371/journal.pone.0021513	en_US
dc.subject.classification	General Science & Technology	en_US
dc.subject.mesh	Arabidopsis	en_US
dc.subject.mesh	MADS Domain Proteins	en_US
dc.subject.mesh	Arabidopsis Proteins	en_US
dc.subject.mesh	Oligoribonucleotides, Antisense	en_US
dc.subject.mesh	Seasons	en_US
dc.subject.mesh	Gene Expression Regulation, Plant	en_US
dc.subject.mesh	Exons	en_US
dc.subject.mesh	Cold Temperature	en_US
dc.subject.mesh	Promoter Regions, Genetic	en_US
dc.title	Vernalization-repression of Arabidopsis FLC requires promoter sequences but not antisense transcripts	en_US
dc.type	Journal Article
utslib.citation.volume	6	en_US
utslib.for	0607 Plant Biology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
utslib.copyright.status	closed_access
pubs.issue	6	en_US
pubs.publication-status	Published	en_US
pubs.volume	6	en_US

Abstract:

The repression of Arabidopsis FLC expression by vernalization (extended cold) has become a model for understanding polycomb-associated epigenetic regulation in plants. Antisense and sense non-coding RNAs have been respectively implicated in initiation and maintenance of FLC repression by vernalization. We show that the promoter and first exon of the FLC gene are sufficient to initiate repression during vernalization; this initial repression of FLC does not require antisense transcription. Long-term maintenance of FLC repression requires additional regions of the gene body, including those encoding sense non-coding transcripts. © 2011 Helliwell et al.

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http://hdl.handle.net/10453/28754