Decreased serum zinc is an effect of ageing and not Alzheimer's disease.

Publication Type:
Journal Article
Citation:
Metallomics : integrated biometal science, 2014, 6 (7), pp. 1216 - 1219
Issue Date:
2014-07
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We examined the distribution of zinc in the periphery (erythrocytes and serum) in a large, well-characterised cohort, the Australian Imaging, Biomarkers and Lifestyle (AIBL) study, in order to determine if there is systemic perturbation in zinc homeostasis in Alzheimer's disease (AD). We observed an age dependent decrease in serum zinc of approximately 0.4% per year. When correcting for the age dependent decline in serum zinc no significant difference between healthy controls (HC), mildly cognitively impaired (MCI) or AD subjects was observed.
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