Smoking Cessation Interventions in Persons Living with HIV or AIDS: A systematic review

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Journal Article
Journal of the Association of Nurses in AIDS Care, 2014, 25 (1), pp. 32 - 45
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Tobacco smoking remains a prevalent behavior in people living with HIV infection (PLWH) and is associated with impaired immune functioning, increased cardiovascular risk, and decreased response to antiretroviral therapy. This review presents a critique and synthesis of evidence on effective smoking cessation interventions for PLWH. A comprehensive search identified 9 peer-reviewed intervention studies, published between 1989 and 2012. The highest odds of smoking cessation (OR 4.33-5.6) were in 2 randomized controlled trial interventions using cell phone technology. Clinically significant reductions in systolic blood pressure, weight gain, and increased CD4+ T cell count were reported for participants who ceased smoking in 3 of the 9 studies. Overall, multi-strategy smoking cessation interventions, delivered over multiple sessions, were effective. However, the most effective interventions were tailored to the unique individual needs of PLWH, including assessment and intervention of poly-substance abuse and mental health issues as well as the inclusion of access-promoting elements.
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