Phytochemical studies on Stemona plants: Isolation of stemofoline alkaloids
- Publication Type:
- Journal Article
- Journal of Natural Products, 2005, 68 (12), pp. 1763 - 1767
- Issue Date:
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Six new stemofoline alkaloids, (2′A)-hydroxystemofoline (5), (3′R)-stemofolenol (6), (3′S)-stemofolenol (7), 1′,2′- didehydrostemofoline-AT-oxide (8), the first C19 stemofoline alkaloid, methylstemofoline (9), and the first glycosidated Stemona alkaloid, stemofolinoside (10), and three known alkaloids, (2′S)-hydroxystemofoline (2), (HZ)-1′,2′-didehydrostemofoline (3), and (11E)-1′, 2′-didehydrostemofoline (4), have been isolated from a root extract of an unidentified Stemona species. The structure and relative configuration of these new alkaloids have been determined by spectral data interpretation and from semisynthetic studies. © 2005 American Chemical Society and American Society of Pharmacognosy.
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