Phytochemical studies on Stemona plants: Isolation of stemofoline alkaloids

Sastraruji, T; Jatisatienr, A; Pyne, SG; Ung, AT; Lie, W; Williams, MC

Phytochemical studies on Stemona plants: Isolation of stemofoline alkaloids

Sastraruji, T Jatisatienr, A Pyne, SG Ung, AT

Lie, W Williams, MC

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Publication Type:: Journal Article
Citation:: Journal of Natural Products, 2005, 68 (12), pp. 1763 - 1767
Issue Date:: 2005-12-01

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Field	Value	Language
dc.contributor.author	Sastraruji, T	en_US
dc.contributor.author	Jatisatienr, A	en_US
dc.contributor.author	Pyne, SG	en_US
dc.contributor.author	Ung, AT https://orcid.org/0000-0002-5665-0702	en_US
dc.contributor.author	Lie, W	en_US
dc.contributor.author	Williams, MC	en_US
dc.date.issued	2005-12-01	en_US
dc.identifier.citation	Journal of Natural Products, 2005, 68 (12), pp. 1763 - 1767	en_US
dc.identifier.issn	0163-3864	en_US
dc.identifier.uri	http://hdl.handle.net/10453/8752
dc.description.abstract	Six new stemofoline alkaloids, (2′A)-hydroxystemofoline (5), (3′R)-stemofolenol (6), (3′S)-stemofolenol (7), 1′,2′- didehydrostemofoline-AT-oxide (8), the first C19 stemofoline alkaloid, methylstemofoline (9), and the first glycosidated Stemona alkaloid, stemofolinoside (10), and three known alkaloids, (2′S)-hydroxystemofoline (2), (HZ)-1′,2′-didehydrostemofoline (3), and (11E)-1′, 2′-didehydrostemofoline (4), have been isolated from a root extract of an unidentified Stemona species. The structure and relative configuration of these new alkaloids have been determined by spectral data interpretation and from semisynthetic studies. © 2005 American Chemical Society and American Society of Pharmacognosy.	en_US
dc.relation.ispartof	Journal of Natural Products	en_US
dc.relation.isbasedon	10.1021/np050361y	en_US
dc.subject.classification	Medicinal & Biomolecular Chemistry	en_US
dc.subject.mesh	Stemonaceae	en_US
dc.subject.mesh	Plant Roots	en_US
dc.subject.mesh	Plants, Medicinal	en_US
dc.subject.mesh	Alkaloids	en_US
dc.subject.mesh	Heterocyclic Compounds, 4 or More Rings	en_US
dc.subject.mesh	Molecular Structure	en_US
dc.subject.mesh	Stereoisomerism	en_US
dc.subject.mesh	Thailand	en_US
dc.title	Phytochemical studies on Stemona plants: Isolation of stemofoline alkaloids	en_US
dc.type	Journal Article
utslib.citation.volume	12	en_US
utslib.citation.volume	68	en_US
utslib.for	0304 Medicinal and Biomolecular Chemistry	en_US
utslib.for	03 Chemical Sciences	en_US
utslib.for	06 Biological Sciences	en_US
utslib.for	11 Medical and Health Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - CCET - Centre for Clean Energy Technology
utslib.copyright.status	closed_access
pubs.issue	12	en_US
pubs.publication-status	Published	en_US
pubs.volume	68	en_US

Abstract:

Six new stemofoline alkaloids, (2′A)-hydroxystemofoline (5), (3′R)-stemofolenol (6), (3′S)-stemofolenol (7), 1′,2′- didehydrostemofoline-AT-oxide (8), the first C19 stemofoline alkaloid, methylstemofoline (9), and the first glycosidated Stemona alkaloid, stemofolinoside (10), and three known alkaloids, (2′S)-hydroxystemofoline (2), (HZ)-1′,2′-didehydrostemofoline (3), and (11E)-1′, 2′-didehydrostemofoline (4), have been isolated from a root extract of an unidentified Stemona species. The structure and relative configuration of these new alkaloids have been determined by spectral data interpretation and from semisynthetic studies. © 2005 American Chemical Society and American Society of Pharmacognosy.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/8752