A new trimethoprim resistance gene, dhfrX, in the In7 integron of plasmid pDGO100.

Publication Type:
Journal Article
Antimicrob Agents Chemother, 1991, 35 (11), pp. 2436 - 2439
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A new trimethoprim resistance determinant, designated dhfrX, was identified in the In7 integron of pDGO100. The sequence of the dhfrX dihydrofolate reductase is up to 28% identical to the sequences of several known dihydrofolate reductase proteins. The dhfrX gene is adjacent to the second 3'-conserved segment of the In7 integron, but the first 77 bases of this segment are not present.
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