First clinical case of a locally acquired carbapenem-resistant VIM-1 metallo-B-lactamase in Pseudomonas aeruginosa in Australia

Australasian Medical Publishing Company Pty. Ltd.
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Journal Article
The Medical Journal of Australia, 2009, 191 (5), pp. 289 - 289
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Nosocomial infections caused by Pseudomonas aeruginosa often prove difficult to treat because of their resistance to multiple drugs. Carbapenems play a pivotal role in the management of severe multidrug-resistant gram-negative Enterobacteriaceae and P. aeruginosa infections. However, reports in Australia of carbapenem resistance due to production of a variety of carbapenemases, including metallo-ß-lactamases (MBLs), have been increasing alarmingly.1,2 We wish to report the first clinical case of a VIM-1-producing MBL in Sydney. To our knowledge, this is the first reported locally acquired case of a P. aeruginosa strain producing acquired VIM-1 MBL in Australia
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