Surface analyses and immune reactivities of major cell wall-associated proteins of group A streptococcus

Amer Soc Microbiology
Publication Type:
Journal Article
Infection And Immunity, 2005, 73 (5), pp. 3137 - 3146
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A proteomic analysis was undertaken to identify cell wall-associated proteins of Streptococcus pyogenes. Seventy-four distinct cell wall-associated proteins were identified, 66 of which were novel. Thirty-three proteins were immunoreactive with pooled S. pyogenes-reactive human antisera. Biotinylation of the GAS cell surface identified 23 cell wall-associated proteins that are surface exposed.
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