New Integron-Associated gene cassette encoding a Trimethoprim-resistant DfrB-Type Dihydrofolate Reductase

American Society for Microbiology
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Journal Article
Antimicrobial agents and chemotherapy, 2006, 50 (8), pp. 2863 - 2865
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A sixth gene cassette containing a dfrB-type gene, dfrB6, was found in a dfrB6-aadA1 cassette array in class 1 integrons. This array was isolated from several multiply antibiotic-resistant Salmonella enterica serovar Infantis strains that appear to be clonally related. The DfrB6 dihydrofolate reductase conferred resistance to trimethoprim.
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