New integron-associated gene cassette encoding a trimethoprim-resistant DfrB-type dihydrofolate reductase

Levings, RS; Lightfoot, D; Elbourne, LDH; Djordjevic, SP; Hall, RM

New integron-associated gene cassette encoding a trimethoprim-resistant DfrB-type dihydrofolate reductase

Levings, RS Lightfoot, D Elbourne, LDH Djordjevic, SP

Hall, RM

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Publication Type:: Journal Article
Citation:: Antimicrobial Agents and Chemotherapy, 2006, 50 (8), pp. 2863 - 2865
Issue Date:: 2006-08-01

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Field	Value	Language
dc.contributor.author	Levings, RS	en_US
dc.contributor.author	Lightfoot, D	en_US
dc.contributor.author	Elbourne, LDH	en_US
dc.contributor.author	Djordjevic, SP https://orcid.org/0000-0001-9301-5372	en_US
dc.contributor.author	Hall, RM	en_US
dc.date.issued	2006-08-01	en_US
dc.identifier.citation	Antimicrobial Agents and Chemotherapy, 2006, 50 (8), pp. 2863 - 2865	en_US
dc.identifier.issn	0066-4804	en_US
dc.identifier.uri	http://hdl.handle.net/10453/9665
dc.description.abstract	A sixth gene cassette containing a dfrB-type gene, dfrB6, was found in a dfrB6-aadA1 cassette array in class 1 integrons. This array was isolated from several multiply antibiotic-resistant Salmonella enterica serovar Infantis strains that appear to be clonally related. The DfrB6 dihydrofolate reductase conferred resistance to trimethoprim. Copyright © 2006, American Society for Microbiology. All Rights Reserved.	en_US
dc.relation.ispartof	Antimicrobial Agents and Chemotherapy	en_US
dc.relation.isbasedon	10.1128/AAC.00449-06	en_US
dc.subject.classification	Microbiology	en_US
dc.subject.mesh	Animals	en_US
dc.subject.mesh	Chickens	en_US
dc.subject.mesh	Dogs	en_US
dc.subject.mesh	Cats	en_US
dc.subject.mesh	Salmonella enterica	en_US
dc.subject.mesh	Trimethoprim	en_US
dc.subject.mesh	Tetrahydrofolate Dehydrogenase	en_US
dc.subject.mesh	Anti-Infective Agents, Urinary	en_US
dc.subject.mesh	Folic Acid Antagonists	en_US
dc.subject.mesh	Serotyping	en_US
dc.subject.mesh	Microbial Sensitivity Tests	en_US
dc.subject.mesh	Drug Resistance, Multiple, Bacterial	en_US
dc.subject.mesh	Trimethoprim Resistance	en_US
dc.subject.mesh	Amino Acid Sequence	en_US
dc.subject.mesh	Base Sequence	en_US
dc.subject.mesh	Integrons	en_US
dc.subject.mesh	Sequence Homology, Amino Acid	en_US
dc.subject.mesh	Genes, Bacterial	en_US
dc.subject.mesh	Molecular Sequence Data	en_US
dc.title	New integron-associated gene cassette encoding a trimethoprim-resistant DfrB-type dihydrofolate reductase	en_US
dc.type	Journal Article
utslib.citation.volume	8	en_US
utslib.citation.volume	50	en_US
utslib.for	0605 Microbiology	en_US
utslib.for	1108 Medical Microbiology	en_US
utslib.for	1115 Pharmacology and Pharmaceutical Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - ithree - Institute of Infection, Immunity and Innovation
utslib.copyright.status	closed_access
pubs.issue	8	en_US
pubs.publication-status	Published	en_US
pubs.volume	50	en_US

Abstract:

A sixth gene cassette containing a dfrB-type gene, dfrB6, was found in a dfrB6-aadA1 cassette array in class 1 integrons. This array was isolated from several multiply antibiotic-resistant Salmonella enterica serovar Infantis strains that appear to be clonally related. The DfrB6 dihydrofolate reductase conferred resistance to trimethoprim. Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/9665