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Showing results 1 to 15 of 15
Issue DateTitleAuthor(s)
2021-03-03A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastomaCheung, BB; Kleynhans, A; Mittra, R; Kim, PY; Holien, JK; Nagy, Z; Ciampa, OC; Seneviratne, JA; Mayoh, C; Raipuria, M; Gadde, S; Massudi, H; Wong, IPL; Tan, O; Gong, A; Suryano, A; Diakiw, SM; Liu, B; Arndt, GM; Liu, T; Kumar, N; Sangfelt, O; Zhu, S; Norris, MD; Haber, M; Carter, DR; Parker, MW; Marshall, GM
2023-05-17Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia.Moles, E; Howard, CB; Huda, P; Karsa, M; McCalmont, H; Kimpton, K; Duly, A; Chen, Y; Huang, Y; Tursky, ML; Ma, D; Bustamante, S; Pickford, R; Connerty, P; Omari, S; Jolly, CJ; Joshi, S; Shen, S; Pimanda, JE; Dolnikov, A; Cheung, LC; Kotecha, RS; Norris, MD; Haber, M; de Bock, CE; Somers, K; Lock, RB; Thurecht, KJ; Kavallaris, M
2019-11-01Drugging MYCN oncogenic signaling through the MYCN-PA2G4 binding interfaceKoach, J; Holien, JK; Massudi, H; Carter, DR; Ciampa, OC; Herath, M; Lim, T; Seneviratne, JA; Milazzo, G; Murray, JE; McCarroll, JA; Liu, B; Mayoh, C; Keenan, B; Stevenson, BW; Gorman, MA; Bell, JL; Doughty, L; Hüttelmaier, S; Oberthuer, A; Fischer, M; Gifford, AJ; Liu, T; Zhang, X; Zhu, S; Gustafson, WC; Haber, M; Norris, MD; Fletcher, JI; Perini, G; Parker, MW; Cheung, BB; Marshall, GM
2021-08-01Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.Xiao, L; Somers, K; Murray, J; Pandher, R; Karsa, M; Ronca, E; Bongers, A; Terry, R; Ehteda, A; Gamble, LD; Issaeva, N; Leonova, KI; O'Connor, A; Mayoh, C; Venkat, P; Quek, H; Brand, J; Kusuma, FK; Pettitt, JA; Mosmann, E; Kearns, A; Eden, G; Alfred, S; Allan, S; Zhai, L; Kamili, A; Gifford, AJ; Carter, DR; Henderson, MJ; Fletcher, JI; Marshall, G; Johnstone, RW; Cesare, AJ; Ziegler, DS; Gudkov, AV; Gurova, KV; Norris, MD; Haber, M
2024-04FDA-approved disulfiram as a novel treatment for aggressive leukemia.Karsa, M; Xiao, L; Ronca, E; Bongers, A; Spurling, D; Karsa, A; Cantilena, S; Mariana, A; Failes, TW; Arndt, GM; Cheung, LC; Kotecha, RS; Sutton, R; Lock, RB; Williams, O; de Boer, J; Haber, M; Norris, MD; Henderson, MJ; Somers, K
2016-06Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis.Carter, DR; Sutton, SK; Pajic, M; Murray, J; Sekyere, EO; Fletcher, J; Beckers, A; De Preter, K; Speleman, F; George, RE; Haber, M; Norris, MD; Cheung, BB; Marshall, GM
2023-04-01Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma.Seneviratne, JA; Carter, DR; Mittra, R; Gifford, A; Kim, PY; Luo, J-S; Mayoh, C; Salib, A; Rahmanto, AS; Murray, J; Cheng, NC; Nagy, Z; Wang, Q; Kleynhans, A; Tan, O; Sutton, SK; Xue, C; Chung, SA; Zhang, Y; Sun, C; Zhang, L; Haber, M; Norris, MD; Fletcher, JI; Liu, T; Dilda, PJ; Hogg, PJ; Cheung, BB; Marshall, GM
2019-01-30Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastomaGamble, LD; Purgato, S; Murray, J; Xiao, L; Yu, DMT; Hanssen, KM; Giorgi, FM; Carter, DR; Gifford, AJ; Valli, E; Milazzo, G; Kamili, A; Mayoh, C; Liu, B; Eden, G; Sarraf, S; Allan, S; Giacomo, SD; Flemming, CL; Russell, AJ; Cheung, BB; Oberthuer, A; London, WB; Fischer, M; Trahair, TN; Fletcher, JI; Marshall, GM; Ziegler, DS; Hogarty, MD; Burns, MR; Perini, G; Norris, MD; Haber, M
2016-01-01The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expressionTee, AE; Liu, B; Song, R; Li, J; Pasquier, E; Cheung, BB; Jiang, C; Marshall, GM; Haber, M; Norris, MD; Fletcher, JI; Dinger, ME; Liu, T
2023-10-25Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma.Zhai, L; Balachandran, A; Larkin, R; Seneviratne, JA; Chung, SA; Lalwani, A; Tsubota, S; Beck, D; Kadomatsu, K; Beckers, A; Durink, K; De Preter, K; Speleman, F; Haber, M; Norris, MD; Swarbrick, A; Cheung, BB; Marshall, GM; Carter, DR
2018-06-15Network modeling of microRNA-mRNA interactions in neuroblastoma tumorigenesis identifies miR-204 as a direct inhibitor of MYCNOoi, CY; Carter, DR; Liu, B; Mayoh, C; Beckers, A; Lalwani, A; Nagy, Z; De Brouwer, S; Decaesteker, B; Hung, TT; Norris, MD; Haber, M; Liu, T; De Preter, K; Speleman, F; Cheung, BB; Marshall, GM
2021-03Targeted Therapy of <i>TERT</i>-Rearranged Neuroblastoma with BET Bromodomain Inhibitor and Proteasome Inhibitor Combination Therapy.Chen, J; Nelson, C; Wong, M; Tee, AE; Liu, PY; La, T; Fletcher, JI; Kamili, A; Mayoh, C; Bartenhagen, C; Trahair, TN; Xu, N; Jayatilleke, N; Wong, M; Peng, H; Atmadibrata, B; Cheung, BB; Lan, Q; Bryan, TM; Mestdagh, P; Vandesompele, J; Combaret, V; Boeva, V; Wang, JY; Janoueix-Lerosey, I; Cowley, MJ; MacKenzie, KL; Dolnikov, A; Li, J; Polly, P; Marshall, GM; Reddel, RR; Norris, MD; Haber, M; Fischer, M; Zhang, XD; Pickett, HA; Liu, T
2020-08Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia.Salik, B; Yi, H; Hassan, N; Santiappillai, N; Vick, B; Connerty, P; Duly, A; Trahair, T; Woo, AJ; Beck, D; Liu, T; Spiekermann, K; Jeremias, I; Wang, J; Kavallaris, M; Haber, M; Norris, MD; Liebermann, DA; D'Andrea, RJ; Murriel, C; Wang, JY
2019-11-05The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35.Liu, PY; Tee, AE; Milazzo, G; Hannan, KM; Maag, J; Mondal, S; Atmadibrata, B; Bartonicek, N; Peng, H; Ho, N; Mayoh, C; Ciaccio, R; Sun, Y; Henderson, MJ; Gao, J; Everaert, C; Hulme, AJ; Wong, M; Lan, Q; Cheung, BB; Shi, L; Wang, JY; Simon, T; Fischer, M; Zhang, XD; Marshall, GM; Norris, MD; Haber, M; Vandesompele, J; Li, J; Mestdagh, P; Hannan, RD; Dinger, ME; Perini, G; Liu, T
2024-07-11The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis.Murray, JE; Valli, E; Milazzo, G; Mayoh, C; Gifford, AJ; Fletcher, JI; Xue, C; Jayatilleke, N; Salehzadeh, F; Gamble, LD; Rouaen, JRC; Carter, DR; Forgham, H; Sekyere, EO; Keating, J; Eden, G; Allan, S; Alfred, S; Kusuma, FK; Clark, A; Webber, H; Russell, AJ; de Weck, A; Kile, BT; Santulli, M; De Rosa, P; Fleuren, EDG; Gao, W; Wilkinson-White, L; Low, JKK; Mackay, JP; Marshall, GM; Hilton, DJ; Giorgi, FM; Koster, J; Perini, G; Haber, M; Norris, MD